000			03388nam a22003615i 4500
001			234770
003			ES-VaUE
005			20221220020624.0
007			cr nn 008mamaa
008			100301s1998 xxu| s |||| 0|eng d
020			_a9781592592562
024	7		_a10.1007/978-1-59259-256-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aNatural Products Isolation _cedited by Richard J. P. Cannell.
250			_a1st edition 1998
264		1	_aTotowa, NJ _bHumana Press _c1998
300			_a1 recurso en línea (480 páginas) _b
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Biotechnology _x1940-607X _v4
505	0		_aHow to Approach the Isolation of a Natural Product -- Initial Extraction and Product Capture -- Supercritical Fluid Methods -- Isolation by Low-Pressure Column Chromatography -- Isolation by Ion-Exchange Methods -- Isolation by Preparative HPLC -- Isolation by Planar Chromatography -- Separation by High-Speed Countercurrent Chromatography -- Crystallization and Final Stages of Purification -- Dereplication and Partial Identification of Natural Products -- Purification of Water-Soluble Natural Products -- Special Problems with the Extraction of Plants -- Isolation of Marine Natural Products -- Scale-Up of Natural Products Isolation -- Follow-Up of Natural Product Isolation.
520			_aNatural Products Isolation provides a comprehensive introduction to techniques for the extraction and purification of natural products from all biological sources. The book opens with an introduction to separations and chromatography and discusses the approach to an isolation. Experienced experimentalists describe a wide array of methods for isolation of both known and unknown natural products, including initial extraction, open column chromatography, HPLC, countercurrent and planar chromatography, SFE, and crystallisation. Later chapters address specific issues in working with plants, marine organisms, water-soluble compounds, as well as scale-up, dereplication and follow-up of a natural product lead. For the less experienced, these chapters provide background information and hands-on advice - using real examples - about how to approach an extraction in general, when and how to apply a particular technique and how to modify conditions according to the nature of the compound being isolated. Geared to scientists with little experience of natural products extraction, but offering even skilled researchers valuable advice and insight, Natural Products Isolation lays the foundation for the potential extractor to isolate natural substances efficiently. Its methods and guidance will almost certainly play a major role in today's natural product discovery and development.
700	1		_aCannell, Richard J. P _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781489942678
776	0	8	_iPrinted edition: _z9780896033627
776	0	8	_iPrinted edition: _z9781489942661
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59259-256-2 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_1998
999			_c234770 _d234770