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020 _a9781493937431
024 7 _a10.1007/978-1-4939-3743-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 4 _aThe Gene Ontology Handbook
_cedited by Christophe Dessimoz, Nives Škunca.
250 _a1st edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (XII, 305 páginas)
_b56 ilustraciones, 50 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1446
505 0 _aPrimer on Ontologies -- The Gene Ontology and the Meaning of Biological Function -- Primer on the Gene Ontology -- Best Practices in Manual Annotation with the Gene Ontology -- Computational Methods for Annotation Transfers from Sequence -- Text Mining to Support Gene Ontology Curation and Vice Versa -- How Does the Scientific Community Contribute to Gene Ontology? -- Evaluating Computational Gene Ontology Annotations -- Evaluating Functional Annotations of Enzymes Using the Gene Ontology -- Community-Based Evaluation of Computational Function Prediction -- Get GO!: Retrieving GO Data Using AmiGO, QuickGO, API, Files, and Tools -- Semantic Similarity in the Gene Ontology -- Gene-Category Analysis -- Gene Ontology: Pitfalls, Biases, and Remedies -- Visualizing GO Annotations -- A Gene Ontology Tutorial in Python -- Annotation Extensions -- The Evidence and Conclusion Ontology (ECO): Supporting GO Annotations -- Complementary Sources of Protein Functional Information: The Far Side of GO -- Integrating Bio-Ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes -- The Vision and Challenges of the Gene Ontology.
506 0 _aOpen Access
520 _aThis book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.
700 1 _aDessimoz, Christophe
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aŠkunca, Nives
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493937417
776 0 8 _iPrinted edition:
_z9781493937424
776 0 8 _iPrinted edition:
_z9781493981267
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3743-1
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2017
999 _c234789
_d234789