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020 _a9781592596485
024 7 _a10.1385/1592596487
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aChiral Separations
_bMethods and Protocols
_cedited by Gerald Gübitz, Martin G. Schmid.
250 _a1st edition 2004
264 1 _aTotowa, NJ
_bHumana Press
_c2004
300 _a1 recurso en línea (XIV, 432 páginas)
_b
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v243
505 0 _aChiral Separation Principles -- Separation of Enantiomers by Thin-Layer Chromatography -- Cyclodextrin-Based Chiral Stationary Phases for Liquid Chromatography -- Enantiomeric Separations by HPLC Using Macrocyclic Glycopeptide-Based Chiral Stationary Phases -- Chiral Separation by HPLC Using Polysaccharide-Based Chiral Stationary Phases -- Applications of Polysaccharide-Based Chiral Stationary Phases for Resolution of Different Compound Classes -- Chiral Separation by HPLC With Pirkle-Type Chiral Stationary Phases -- Chiral Separation by HPLC Using the Ligand-Exchange Principle -- Chiral Separations by HPLC Using Molecularly Imprinted Polymers -- Indirect Enantioseparation by HPLC Using Chiral Benzofurazan-Bearing Reagents -- Separation of Racemic Trans-Stilbene Oxide by Sub-/Supercritical Fluid Chromatography -- Chiral Separations Using the Macrocyclic Antibiotics in Capillary Electrophoresis -- Enantioresolutions by Capillary Electrophoresis Using Glycopeptide Antibiotics -- Separation of Enantiomers by Capillary Electrophoresis Using Cyclodextrins -- Chiral Separations by Capillary Electrophoresis Using Proteins as Chiral Selectors -- Cellulases as Chiral Selectors in Capillary Electrophoresis -- Use of Chiral Crown Ethers in Capillary Electrophoresis -- Chiral Separations by Capillary Electrophoresis Using Cinchona Alkaloid Derivatives as Chiral Counter-Ions -- Chiral Separation by Capillary Electrophoresis Using Polysaccharides -- Chiral Micellar Electrokinetic Chromatography -- Chiral Separation by Capillary Electrophoresis in Nonaqueous Medium -- Chiral Ligand-Exchange Capillary Electrophoresis and Capillary Electrochromatography -- Enantioseparation in Capillary Chromatography and Capillary Electrochromatography Using Polysaccharide-Type Chiral Stationary Phases -- Chiral Separation by Capillary Electrochromatography Using Cyclodextrin Phases -- Chiral Separations by Capillary Electrochromatography Using Molecularly Imprinted Polymers.
520 _aMethods for enantiomer separation are very important for controlling synthesis, for checking racemization, for enantiomeric purity control, and for pharmacokinetic studies. In Chiral Separations: Methods and Protocols, prominent experts from around the world detail the chromatographic and electroseparation techniques they have developed for chiral separations on an analytical scale. Described in step-by-step detail to ensure successful experimental results, the procedures are presented as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques, but also including thin layer chromotogrphic, gas chromatographic, and supercritical fluid chromatographic as well as recent electrochromotographic techniques. Each fully tested protocol includes an introduction to the principle underlying the method, equipment and reagent lists, and helpful notes on troubleshooting and avoiding known pitfalls. Up-to-date and highly practical, Chiral Separations: Methods and Protocols will help both novice and advanced users not only choose optimal methods for their separation problems, but also readily obtain successful results.
700 1 _aGübitz, Gerald
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSchmid, Martin G
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781617373909
776 0 8 _iPrinted edition:
_z9781588291509
776 0 8 _iPrinted edition:
_z9781489939333
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592596487
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2004
999 _c234800
_d234800