000			03825nam a22003735i 4500
001			234879
003			ES-VaUE
005			20221220020630.0
007			cr nn 008mamaa
008			100301s2004 xxu| s |||| 0|eng d
020			_a9781592597635
024	7		_a10.1385/1592597637 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aGenomics, Proteomics, and Clinical Bacteriology _bMethods and Reviews _cedited by Neil Woodford, Alan P. Johnson.
250			_a1st edition 2004
264		1	_aTotowa, NJ _bHumana Press _c2004
300			_a1 recurso en línea (X, 398 páginas) _b
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v266
505	0		_aPrinciples of Bacterial Genomics -- Bacterial Genomes for the Masses -- Public Databases -- Genome Sequencing and Annotation -- Comparative Genomics -- Genome Plasticity -- Exploring and Exploiting Bacterial Proteomes -- Application of Genomics to Diagnostic Bacteriology -- Molecular Diagnostics -- Molecular Diagnostics -- Real-Time PCR -- Microarrays for Bacterial Typing -- Interrogating Bacterial Genomes -- Genomic Approaches to Antibacterial Discovery -- Using the Genome to Understand Pathogenicity -- Identification of Novel Pathogenicity Genes by PCR Signature-Tagged Mutagenesis and Related Technologies -- Discovering New Pathogens -- Exploring the Concept of Clonality in Bacteria -- Bacterial Taxonomics.
520			_aIt is essential that all clinical bacteriologists become active participants in the current genomics and proteomics revolution if the significant achievements of genome sequencing and analysis are to produce real benefits for patient care. In Genomics, Proteomics, and Clinical Bacteriology, a panel of internationally renowned experts reviews how genomics has provided novel methods for bacterial investigation and advanced our knowledge of bacterial pathogenicity. The authors critically evaluate the applications of genomics to diagnostic bacteriology, highlighting both current and likely future uses, describing real-time PCR methods, and outlining the promise of microarrays in clinical bacteriology. Their discussion examines in detail genomic approaches to antibacterial discovery, the nature of pathogenicity, the discovery of new pathogens, the exploration of the concept of clonality in bacteria, and bacterial taxonomics. Introductory material explains for the uninitiated the relevance of genomics to the clinical laboratory, illustrating the art and science of working with public databases, digging for data, and exploiting bacterial proteomes. Comprehensive and insightful, Genomics, Proteomics, and Clinical Bacteriology offers everyone working in medical bacteriology an accessible introduction to a rapidly evolving discipline, one that shows not only how knowledge of bacterial genome sequences affects diagnostic bacteriology today, but also how that knowledge may be used in the future to gain new insights into bacterial disease processes, identify critical targets for antiinfectives, and aid in designing novel antibiotics.
700	1		_aWoodford, Neil _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aJohnson, Alan P _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781617374289
776	0	8	_iPrinted edition: _z9781489939739
776	0	8	_iPrinted edition: _z9781588292186
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592597637 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2004
999			_c234879 _d234879