000			04151nam a22003615i 4500
001			234909
003			ES-VaUE
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007			cr nn 008mamaa
008			100917s2010 xxu| s |||| 0|eng d
020			_a9781607618003
024	7		_a10.1007/978-1-60761-800-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aSystems Biology in Drug Discovery and Development _bMethods and Protocols _cedited by Qing Yan.
250			_a1st edition 2010
264		1	_aTotowa, NJ _bHumana Press _c2010
300			_a1 recurso en línea (XII, 337 páginas) _b36 ilustraciones, 6 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v662
505	0		_aMethodologies of Systems Biology in Drug Discovery and Development -- Proteomics and Systems Biology: Application in Drug Discovery and Development -- Systems Biology Approaches and Tools for Analysis of Interactomes and Multi-target Drugs -- Systems Biology "On-the-Fly": SILAC-Based Quantitative Proteomics and RNAi Approach in Drosophila melanogaster -- Systems Biology of Cell Behavior -- Computational Modeling in Systems Biology -- An Introduction to Gaussian Bayesian Networks -- Derivation of Large-Scale Cellular Regulatory Networks from Biological Time Series Data -- Translational Bioinformatics and Systems Biology Approaches for Personalized Medicine -- Systems Biology Methods for Disease Treatment and Translational Medicine -- Systems Biology and Inflammation -- Immunoinformatics and Systems Biology Methods for Personalized Medicine -- Systems Biology Approaches to the Study of Cardiovascular Drugs -- Cancer Systems Biology -- Systemic Lupus Erythematosus: From Genes to Organ Damage -- Systems Biology of Influenza: Understanding Multidimensional Interactions for Personalized Prevention and Treatment -- Methods in Systems Biology of Experimental Methamphetamine Drug Abuse -- Systems Biology and Theranostic Approach to Drug Discovery and Development to Treat Traumatic Brain Injury -- Erratum to: Cancer Systems Biology -- Erratum to: Cancer Systems Biology.
520			_aDue to the failing "one-drug-fits-all" model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine.
700	1		_aYan, Qing _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781607617990
776	0	8	_iPrinted edition: _z9781607618010
776	0	8	_iPrinted edition: _z9781493957705
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60761-800-3 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2010
999			_c234909 _d234909