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020 _a9781493937653
024 7 _a10.1007/978-1-4939-3765-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aNeurotransmitter Transporters
_bInvestigative Methods
_cedited by Heinz Bönisch, Harald H. Sitte.
250 _a1st edition 2016
264 1 _aNew York, NY
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XIII, 229 páginas)
_b48 ilustraciones, 25 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aNeuromethods
_x1940-6045
_v118
505 0 _aClassical Radioligand Uptake and Binding Methods in Transporter Research: An Emphasis on the Monoamine Neurotransmitter Transporters -- Tracer Flux Measurements to Study Outward Transport by Monoamine Neurotransmitter Transporters -- Interrogating the Activity of Ligands at Monoamine Transporters in Rat Brain Synaptosomes.-- Using High-Speed Chronoamperometry to Measure Biogenic Amine Release and Uptake In Vivo -- Experimental Data Guided Docking of Small Molecules Into Homology Models Of Neurotransmitter Transporters -- Immunohistochemical Methods for the Study of the Expression of Low-Affinity Monoamine Transporters in the Brain -- Analysis of Neurotransmitter Transporter Posttranslational Modifications: Phosphorylation and Palmitoylation -- Ensemble and Single Quantum Dot Fluorescence Methods in Neurotransmitter Transporter Research -- Approaches for Investigating Transporter Endocytic Trafficking In Cell Lines and Native Preparations -- Organic Cation Transport Measurements Using Fluorescence Techniques -- Animal Models for Depression and the Mode of Action of Neurotransmitter Transporter-Blocking Antidepressants -- In-Vivo Imaging of Dopamine Metabolism and Dopamine Transporter Function in the Human Brain. .
520 _aThe volume aims at providing an overview of cutting-edge methods and protocols used in neuroscience and neurological research. Neurotransmitter Transporters: Investigative Methods will be of interest to scientists, graduate students, and advanced undergraduates who seek an overview of methods and protocols in this field of neuroscience. It will also be of interest to physicians who are carrying out imaging and postmortem studies of neurotransmitter transporters in the human brain. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Neurotransmitter Transporters: Investigative Methods aims to ensure successful results in the further study of this vital field.
700 1 _aBönisch, Heinz
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSitte, Harald H
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493937639
776 0 8 _iPrinted edition:
_z9781493937646
776 0 8 _iPrinted edition:
_z9781493981328
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3765-3
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2016
999 _c234915
_d234915