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020 _a9781493921553
024 7 _a10.1007/978-1-4939-2155-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aEpistasis
_bMethods and Protocols
_cedited by Jason H. Moore, Scott M. Williams.
250 _a1st edition 2015
264 1 _aNew York, NY
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (X, 350 páginas)
_b61 ilustraciones, 17 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1253
505 0 _aLong Term Selection Experiments: Epistasis and The Response To Selection -- Finding the Epistasis Needles in the Genome-Wide Haystack -- Biological Knowledge-Driven Analysis of Epistasis in Human GWAS with Application to Lipid Traits -- Epistasis for Quantitative Traits in Drosophila -- Epistasis In The Risk Of Human Neuropsychiatric Disease -- On the Partitioning of Genetic Variance with Epistasis -- Measuring Gene Interactions -- Two Rules for the Detection and Quantification of Epistasis and other Interaction Effects -- Direct Approach to Modeling Epistasis -- Capacitating Epistasis  - Detection and Role in the Genetic Architecture of Complex Traits -- Compositional Epistasis: An Epidemiologic Perspective -- Identification Of Genome-Wide SNP-SNP and SNP-Clinical Boolean Interactions In Age-Related Macular Degeneration -- Epistasis Analysis Using Information Theory -- Genome-Wide Epistasis and Pleiotropy Characterized by the Bipartite Human -- Network Theory for Data-Driven Epistasis Networks --  Epistasis Analysis Using Multifactor Dimensionality Reduction --  Epistasis Analysis Using ReliefF -- Epistasis Analysis Using Artificial Intelligence.
520 _aThis volume presents a valuable and readily reproducible collection of established and emerging techniques on modern genetic analyses. Chapters focus on statistical or data mining analyses, genetic architecture, the burden of multiple testing, genetic variance, measuring epistasis, multifactor dimensionality reduction, and ReliefF. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Epistasis: Methods and Protocols aids scientists in continuing to study elucidate epistasis in the context of modern data availability.
700 1 _aMoore, Jason H
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWilliams, Scott M
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493921560
776 0 8 _iPrinted edition:
_z9781493921546
776 0 8 _iPrinted edition:
_z9781493942756
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2155-3
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2015
999 _c234918
_d234918