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020 _a9781627035170
024 7 _a10.1007/978-1-62703-517-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aMultidisciplinary Tools for Investigating Synaptic Plasticity
_cedited by Peter V. Nguyen.
250 _a1st edition 2013
264 1 _aTotowa, NJ
_bHumana Press
_c2013
300 _a1 recurso en línea (XIV, 274 páginas)
_b55 ilustraciones, 27 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aNeuromethods
_x1940-6045
_v81
505 0 _aConditional Gene Targeting: A Refined Method for Genetic Studies in Neurosciences -- Sindbis Virus-Mediated In Vivo Expression of Recombinant CREB to Study Gene Function in Neuronal Plasticity and Behavior -- Exploring Mechanisms of Synaptic Plasticity Using Exogenous Expression of Proteins at the Sensory-to-Motor Neuron Synapse of Aplysia -- Translational Regulation of Synaptic Plasticity -- Glutamate Receptors and Synaptic Physiology in Developing Neural Circuits -- Laminar Quantification of Dendrites in Dentate Gyrus Granule Neurons -- Electrophysiological and Biochemical Studies of AMPA Receptor Phosphorylation and Synaptic Plasticity in Hippocampal CA1 Mini-Slices -- Electrophysiological and Behavioral Approaches to the Analysis of Synaptic Tagging and Capture -- Intracellular Loading and Rapid Calcium Imaging in Processes of Hippocampal Astrocytes -- Electrophysiological Methods for Investigating Inhibitory Synaptic Plasticity -- Converging Methodologies in a Mammalian 'Simple System' Focused on the Biology of Memory: Conditioned Odor Preference in the Neonate Rat -- The Sagittally-Sectioned Rat Hindbrain Preparation: Improved Access to the Brainstem Respiratory Network.
520 _aInvestigations involving incisive mechanistic dissection of various types of synaptic plasticity have revealed that it plays key roles in neural development, sensory information processing, cortical remapping following brain injury, perception, and behavioral learning and memory. Disruptions of synaptic plasticity may underlie neurological and behavioral disorders such as Alzheimer disease, Fragile-X syndrome,  autism, and drug addiction. Multidisciplinary Tools for Investigating Synaptic Plasticity, therefore, assembles expert contributions that highlight techniques and strategies used in probing the cellular and molecular mechanisms of synaptic plasticity in the nervous systems of vertebrate and invertebrate species. Divided into three sections, this meticulous volume describes biochemical and genetic strategies for studying synaptic plasticity, behavior, neural development, and synaptogenesis, and also includes cellular electrophysiological and optical methods for interrogating a diverse array of mechanistic issues. As part of the Neuromethods series, this book contains the kind of detail and key implementation advice that maximizes successful results.   Authoritative and invaluable, Multidisciplinary Tools for Investigating Synaptic Plasticity serves as an ideal primer for introducing researchers to specific techniques that will enhance their success at addressing novel questions in synaptic plasticity at the lab bench.
700 1 _aNguyen, Peter V
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781627035187
776 0 8 _iPrinted edition:
_z9781627035163
776 0 8 _iPrinted edition:
_z9781493959198
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-517-0
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2013
999 _c234934
_d234934