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001			234965
003			ES-VaUE
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007			cr nn 008mamaa
008			100301s2008 xxu| s |||| 0|eng d
020			_a9781597454391
024	7		_a10.1007/978-1-59745-439-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aPharmacogenomics and Personalized Medicine _cedited by Nadine Cohen.
250			_a1st edition 2008
264		1	_aTotowa, NJ _bHumana Press _c2008
300			_a1 recurso en línea (XVI, 509 páginas) _b53 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aChallenges, Opportunities, and Evolving Landscapes in Pharmacogenomics and Personalized Medicine -- Implementation of Pharmacogenomic Sample Collection in Clinical Trials -- Pharmacogenomics -- Applications of Pharmacogenomics in Drug Discovery -- Applications of Pharmacogenomics in Clinical Trials -- Pharmacogenomics Applications in Drug Metabolism -- The Genetics of Adverse Drug Reactions -- Strategies and Resources for Marker Selection and Genotyping in Genetic Association Studies -- Study Design and Statistical Issues in Pharmacogenetics Research -- Holy SNP, Batman! -- Predictive Biomarker Classifiers in the Design of Pivotal Clinical Trials -- Translation of Biomarkers into Clinical Utility -- Pharmacogenomic Study Feasibility Assessment and Pharmaceutical Business Decision-Making -- Co-Development of Drugs and Pharmacogenomics-Based Diagnostics in Oncology -- Pharmacogenomics Applications in Epilepsy Chantal Depondt -- Pharmacogenomics in Alzheimer's Disease -- Pharmacogenomics Applications in Psychiatric Disorders -- Pharmacogenomics in HIV Disease -- Pharmacogenomics and Cardiovascular Drugs -- Pharmacogenomic Applications in Children -- Pharmacogenomics of Rare and Monogenic Disorders.
520			_aWith all of the multitude of challenges facing the pharmaceutical research and development process, the industry is actively exploring the relationships between human genetics and drug responsiveness, susceptibility to disease and disease severity. In Pharmacogenomics and Personalized Medicine, leading experts from the pharmaceutical industry, the scientific community and the government provide guidance for conducting pharmacogenomic research from discovery to the market, while also presenting a realistic perspective on the challenges, practicalities and obstacles in its application. Focusing on DNA data and associated analytical methodologies this volume includes a wide array of vital, cutting-edge research. Comprehensive and timely, Pharmacogenomics and Personalized Medicine will assist novice and experienced investigators alike in the understanding of the current scientific challenges in applying pharmacogenomics to drug discovery and clinical development.
700	1		_aCohen, Nadine _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781603278973
776	0	8	_iPrinted edition: _z9781617379215
776	0	8	_iPrinted edition: _z9781934115046
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-439-1 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2008
999			_c234965 _d234965