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008			131121s2014 xxu| s |||| 0|eng d
020			_a9781461492276
024	7		_a10.1007/978-1-4614-9227-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aCancer Prevention _bDietary Factors and Pharmacology _cedited by Ann M. Bode, Zigang Dong.
250			_a1st edition 2014
264		1	_aNew York, NY _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XV, 288 páginas) _b48 ilustraciones, 32 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aCombining Computational and Experimental Methods for Identifying Molecular Targets of Phytochemicals -- Common Methods Used for the Discovery of Natural Anticancer Compounds -- Nrf2-Target Approaches in Cancer Chemoprevention Mediated by Dietary Phytochemicals -- Methods to Analyze Chemopreventive Effect of Silibinin on Prostate Cancer Biomarkers Protein Expression -- An Approach to the Evaluation of Berries for Cancer Prevention with Emphasis on Esophageal Cancer -- The Use of Mouse Models for Lung Cancer Chemoprevention Studies -- The Azoxymethane Plus Dextran Sulfate Sodium-Induced Mouse Colon Cancer Model for the Study of Dietary Chemoprevention of Inflammation-Associated Carcinogenesis -- The Use of Seahorse Extracellular Flux Analyzer in Mechanistic Studies of Naturally-Occurring Cancer Chemopreventive Agents -- Utilizing RNA-Seq to Define Phytochemical-Induced Alterations in Insulin and IGF Regulated Transcriptomes -- The Ex Vivo Use of Keratinocytes from Adult Mice to Define Stem Cell Activities in Cancer Research -- Quantitation of Acetaldehyde-DNA Adducts: Biomarkers of Alcohol Consumption -- Imaging Tools in Discovery and Development of Phytochemical Chemopreventive Agents -- Designing the Chemoprevention Trials of Tomorrow: Applying Lessons Learned from Past Definitive Trials.
520			_aFocused on the discovery of precise molecular targets for the development of the cancer preventive agents, Cancer Prevention: Dietary Factors and Pharmacology provides researchers and non-researchers with practical methodologies for developing and validating small molecule and phytochemical-derived drug discovery and mechanisms by which these compounds can modulate distinct target proteins involved in oncogenic signaling. While this volume is primarily focused toward cancer prevention research, the range of techniques demonstrated in the book also provides an introduction of cancer prevention research methods to researchers outside the field. Chapters deal with a critical discussion of both laboratory and clinical topics, with each chapter containing both a discursive section along with a detailed methods section. As part of the Methods in Pharmacology and Toxicology series, this meticulous volume includes the kind of key implementation advice that seeks to ensure successful results in the lab. Practical and authoritative, Cancer Prevention: Dietary Factors and Pharmacology aims to guide research toward identifying molecular targets and conducting human studies with phytochemicals which would, ideally, provide an enhanced approach to the goal of personalized cancer prevention.
700	1		_aBode, Ann M _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aDong, Zigang _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781461492283
776	0	8	_iPrinted edition: _z9781461492269
776	0	8	_iPrinted edition: _z9781493954469
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4614-9227-6 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2014
999			_c234976 _d234976