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020 _a9781607611752
024 7 _a10.1007/978-1-60761-175-2
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aProtein Networks and Pathway Analysis
_cedited by Yuri Nikolsky, Julie Bryant.
250 _a1st edition 2009
264 1 _aTotowa, NJ
_bHumana Press
_c2009
300 _a1 recurso en línea (XIV, 410 páginas)
_b118 ilustraciones
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v563
505 0 _aI: Interactions -- Mining Protein-Protein Interactions from Published Literature Using Linguamatics I2E -- Relative Avidity, Specificity, and Sensitivity of Transcription Factor-DNA Binding in Genome-Scale Experiments -- Curation of Inhibitor-Target Data: Process and Impact on Pathway Analysis -- Profiling Protein Interaction Networks with Functional Protein Microarrays -- Manual Annotation of Protein Interactions -- II: Analysis -- Gene Set Enrichment Analysis -- PANTHER Pathway: An Ontology-Based Pathway Database Coupled with Data Analysis Tools -- Prioritizing Genes for Pathway Impact Using Network Analysis -- Discovering Biological Networks from Diverse Functional Genomic Data -- Functional Analysis of OMICs Data and Small Molecule Compounds in an Integrated "Knowledge-Based" Platform -- Kinetic Modeling as a Tool to Integrate Multilevel Dynamic Experimental Data -- Cytoscape: A Community-Based Framework for Network Modeling -- Semantic Data Integration and Knowledge Management to Represent Biological Network Associations -- Solutions for Complex, Multi Data Type and Multi Tool Analysis: Principles and Applications of Using Workflow and Pipelining Methods -- III: Applications -- High-Throughput siRNA Screening as a Method of Perturbation of Biological Systems and Identification of Targeted Pathways Coupled with Compound Screening -- Pathway and Network Analysis with High-Density Allelic Association Data -- miRNAs: From Biogenesis to Networks -- MetaMiner (CF): A Disease-Oriented Bioinformatics Analysis Environment -- Translational Research and Biomedical Informatics -- ArrayTrack: An FDA and Public Genomic Tool.
520 _aFrom the beginning of the OMICs biology era, science has been pursuing the reduction of the complex "genome-wide" assays in order to understand the essential biology that lies beneath it.  In Protein Networks and Pathway Analysis, expert practitioners present a compilation of methods of functional data analysis, often referred to as "systems biology," and its applications in drug discovery, medicine and basic disease research.  The volume is divided into three convenient sections, covering the elucidation of protein, compound and gene interactions, analytical tools, including networks, interactome and ontologies, and applications of functional analysis.  As a volume in the highly successful Methods in Molecular Biology™ series, this work provides detailed descriptions and hands-on implementation advice.   Authoritative and cutting-edge, Protein Networks and Pathway Analysis presents both "wet lab" experimental methods and computational tools in order to cover a broad spectrum of issues in this fascinating new field.
700 1 _aNikolsky, Yuri
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aBryant, Julie
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781607611769
776 0 8 _iPrinted edition:
_z9781617794889
776 0 8 _iPrinted edition:
_z9781607611745
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60761-175-2
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2009
999 _c234986
_d234986