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008 120222s2012 xxu| s |||| 0|eng d
020 _a9781617796128
024 7 _a10.1007/978-1-61779-612-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aCancer Epigenetics
_bMethods and Protocols
_cedited by Ramona G. Dumitrescu, Mukesh Verma.
250 _a1st edition 2012
264 1 _aTotowa, NJ
_bHumana Press
_c2012
300 _a1 recurso en línea (XIII, 492 páginas)
_b42 ilustraciones, 32 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v863
520 _aThe epigenetic regulation plays an important role in normal development and maintenance of tissue specific genes expression in humans and the disturbance of these patterns lead to changes involved in tumor formation. More recently, epigenetic changes have been observed in early stages of tumor development and together with the genetic alterations have been defined as abnormalities, necessary for cancer initiation and progression. In, Cancer Epigenetics: Methods and Protocols, expert researchers reviewed these epigenetics changes in different tumor types and described several technologies that are currently available to detect epigenetic changes. These technologies have lead to a better understanding of the processes in normal and cancerous cells. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Cancer Epigenetics: Methods and Protocols aids scientists in continuing to study epigenetic alterations  used in clinical practice as biomarkers of early cancerous lesions or markers of progression and prognosis.
700 1 _aDumitrescu, Ramona G
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aVerma, Mukesh
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781617796111
776 0 8 _iPrinted edition:
_z9781617796135
776 0 8 _iPrinted edition:
_z9781493962044
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-612-8
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2012
999 _c235039
_d235039