000			03544nam a22003495i 4500
001			235067
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007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9781597455046
024	7		_a10.1007/978-1-59745-504-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aNeuroprotection Methods and Protocols _cedited by Tiziana Borsello.
250			_a1st edition 2007
264		1	_aTotowa, NJ _bHumana Press _c2007
300			_a1 recurso en línea (XII, 239 páginas) _b48 ilustraciones, 3 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v399
505	0		_aNeuronal Death and Neuroprotection: A Review -- The Use of Propidium Iodide to Assess Excitotoxic Neuronal Death in Primary Mixed Cortical Cultures -- A Modified Silver Technique (de Olmos Stain) for Assessment of Neuronal and Axonal Degeneration -- Model of Acute Injury to Study Neuroprotection -- Organotypic Entorhino-Hippocampal Slice Cultures-A Tool to Study the Molecular and Cellular Regulation of Axonal Regeneration and Collateral Sprouting In Vitro -- Role of Nrf2-Dependent ARE-Driven Antioxidant Pathway in Neuroprotection -- Biochemical Methods to Assess the Coupling of Brain Energy Metabolism in Control and Disease States -- A Method for Isolating Prosurvival Targets of NF-?B/Rel Transcription Factors -- Functional Cloning of Genes Regulating Apoptosis in Neuronal Cells -- Characterization of mRNA Expression in Single Neurons -- Brain on a Chip: A Method to Detect Novel Neuroprotective Candidate Targets -- Intracerebral Infusion of Neurotrophic Factors -- Synthesis of Cell-Penetrating Peptides and Their Application in Neurobiology -- The Stem Cells as a Potential Treatment for Neurodegeneration -- In Vivo Tomographic Imaging Studies of Neurodegeneration and Neuroprotection: A Review.
520			_aDue to an aging population, the incidence of age-related neurodegenerative diseases is expected to rise dramatically. In Neuroprotection Methods and Protocols, a team of skilled, renowned researchers provide step-by-step laboratory protocols intended to slow or prevent the progression of such diseases. Focusing on neuroprotective approaches, this volume describes basic scientific discoveries and the application of such research within different laboratories in a clear and systematic way in order to orient scientists in this complicated field. The chapters follow the Methods in Molecular Biology™ series format, consisting of readily reproducible methods, lists of the necessary materials, and a Notes section which aids the researcher in solving and avoiding technical problems. Comprehensive and easy to use, Neuroprotection Methods and Protocols is the perfect reference for basic neuroscientists hoping to move forward the ever-important field of neuroprotection and neuronal death research. .
700	1		_aBorsello, Tiziana _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781617377075
776	0	8	_iPrinted edition: _z9781588296665
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-504-6 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2007
999			_c235067 _d235067