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020 _a9781493967407
024 7 _a10.1007/978-1-4939-6740-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aProteome Bioinformatics
_cedited by Shivakumar Keerthikumar, Suresh Mathivanan.
250 _a1st edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (XI, 233 páginas)
_b51 ilustraciones, 40 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1549
505 0 _aAn Introduction to Proteome Bioinformatics -- Proteomic Data Storage and Sharing -- Choosing an Optimal Database for Protein Identification from Tandem Mass Spectrometry Data -- Label-Based and Label-Free Strategies for Protein Quantitation -- TMT One Stop Shop: From Reliable Sample Preparation to Computational Analysis Platform -- Unassigned MS/MS Spectra: Who Am I? -- Methods to Calculate Spectrum Similarity -- Proteotypic Peptides and Their Applications -- Statistical Evaluation of Labeled Comparative Profiling Proteomics Experiments Using Permutation Test -- De Novo Peptide Sequencing: Deep Mining of High-Resolution Mass Spectrometry Data -- Phylogenetic Analysis Using Protein Mass Spectrometry -- Bioinformatics Methods to Deduce Biological Interpretation from Proteomics Data -- A Systematic Bioinformatics Approach to Identify High Quality Mass Spectrometry Data and Functionally Annotate Proteins and Proteomes -- Network Tools for the Analysis of Proteomic Data -- Determining the Significance of Protein Network Features and Attributes Using Permutation Testing -- Bioinformatics Tools and Resources for Analyzing Protein Structures -- In Silico Approach to Identify Potential Inhibitors for Axl-Gas6 Signalling.
520 _aThis thorough book covers the most recent proteomics techniques, databases, bioinformatics tools, and computational approaches that are used for the identification and functional annotation of proteins and their structure. The most recent proteomic resources widely used in the biomedical scientific community for storage and dissemination of data are discussed. In addition, specific MS/MS spectrum similarity scoring functions and their application in the field of proteomics, statistical evaluation of labeled comparative proteomics using permutation testing, and methods of phylogenetic analysis using MS data are also described in detail. Written for the highly successful Methods in Molecular Biology series, chapters contain the kind of detail and key implementation advice to ensure successful results. Authoritative and cutting-edge, Proteome Bioinformatics serves as a useful resource for researchers who are beginners as well as advanced investigators in the field of proteomics.
700 1 _aKeerthikumar, Shivakumar
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMathivanan, Suresh
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493967384
776 0 8 _iPrinted edition:
_z9781493967391
776 0 8 _iPrinted edition:
_z9781493982882
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-6740-7
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2017
999 _c235089
_d235089