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001			235092
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007			cr nn 008mamaa
008			110414s2009 xxu| s |||| 0|eng d
020			_a9781603272582
024	7		_a10.1007/978-1-60327-258-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aHigh Throughput Screening _bMethods and Protocols _cedited by William P. Janzen, Paul Bernasconi.
250			_a2nd edition 2009
264		1	_aTotowa, NJ _bHumana Press _c2009
300			_a1 recurso en línea (XII, 268 páginas) _b98 ilustraciones, 4 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v565
505	0		_aDesign and Implementation of High-Throughput Screening Assays -- Creation of a Small High-Throughput Screening Facility -- Informatics in Compound Library Management -- Statistics and Decision Making in High-Throughput Screening -- Enzyme Assay Design for High-Throughput Screening -- Application of Fluorescence Polarization in HTS Assays -- Screening G Protein-Coupled Receptors: Measurement of Intracellular Calcium Using the Fluorometric Imaging Plate Reader -- High-Throughput Automated Confocal Microscopy Imaging Screen of a Kinase-Focused Library to Identify p38 Mitogen-Activated Protein Kinase Inhibitors Using the GE InCell 3000 Analyzer -- Recent Advances in Electrophysiology-Based Screening Technology and the Impact upon Ion Channel Discovery Research -- Automated Patch Clamping Using the QPatch -- High-Throughput Screening of the Cyclic AMP-Dependent Protein Kinase (PKA) Using the Caliper Microfluidic Platform -- Use of Primary Human Cells in High-Throughput Screens.
520			_aIn the years since the release of the popular first edition, the field of High Throughput Screening (HTS) has evolved considerably, from a small niche area of study to a major, essential scientific technique. In High Throughput Screening: Methods and Protocols, Second Edition, experts in the field fully update the previous edition to best serve as an introduction to HTS for scientists who are just entering the field, and as a provider of key, significant detail so as to be useful to scientists in established HTS operations. Featuring new screening technologies as well as many well established methods, chapters offer comprehensive treatment of the activities directly related to HTS, such as compound library management, data handling, and robotics. As a volume in the highly successful Methods in Molecular Biology™ series, this work provides the kind of meticulous description and implementation advice that is crucial for getting optimal results. Authoritative and intrinsically practical, High Throughput Screening: Methods and Protocols, Second Edition promises to share the highest knowledge and enthusiasm with all those who use this versatile technology in their own labs.
700	1		_aJanzen, William P _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aBernasconi, Paul _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781607611684
776	0	8	_iPrinted edition: _z9781617794919
776	0	8	_iPrinted edition: _z9781603272575
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60327-258-2 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2009
999			_c235092 _d235092