000			03879nam a22003855i 4500
001			235128
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007			cr nn 008mamaa
008			130813s2013 xxu| s |||| 0|eng d
020			_a9781627035446
024	7		_a10.1007/978-1-62703-544-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aPeptide Synthesis and Applications _cedited by Knud J. Jensen, Pernille Tofteng Shelton, Søren L. Pedersen.
250			_a2nd edition 2013
264		1	_aTotowa, NJ _bHumana Press _c2013
300			_a1 recurso en línea (X, 253 páginas) _b68 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1047
505	0		_aSolid-Phase Peptide Synthesis: An Introduction -- Linkers, Resins and General Procedures for Solid-phase Peptide Synthesis -- Peptide Release, Side-chain Deprotection, Work-up, and Isolation -- Synthesis of Peptides using Tert-butyloxycarbonyl (Boc) as the α-amino Protection Group -- Sequential Formation of Regioselective Disulfide Bonds in Synthetic Peptides with Multiple Disulfide Bonds -- Synthesis of Cyclic Disulfide-Rich Peptides -- Preparation of C-terminally Modified Chemokines by Expressed Protein Ligation -- Synthesis of C-terminal Peptide Thioesters using Fmoc Based Solid-phase Peptide Chemistry -- Backbone Amide Linker Strategy -Protocols for the Synthesis of C‑terminal Peptide Aldehydes -- Synthesis of N-methylated Peptides: On-resin Methylation and Microwave-Assisted Couplings -- Synthesis of Antimicrobial Peptoids -- Synthesis of Lipidated Peptides -- Solid-Phase Synthesis of Phosphopeptides -- Synthesis of O-Glycopeptides and Construction of Glycopeptide Microarrays -- Instruments for Automated Peptide Synthesis -- Microwave-Assisted Solid-Phase Peptide Synthesis using the Biotage Syro Wave™ -- Microwave-Assisted Solid-Phase Peptide Synthesis Based on the Fmoc Protecting Group Strategy (CEM).
520			_aPeptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging.  The second edition of  Peptide Synthesis and Applications expands upon the previous editions with current, detailed methodologies for peptide synthesis. With new chapters on laboratory protocols for both the specialist and the non-specialist. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Peptide Synthesis and Application, Second Edition seeks to aid scientists in understanding different approaches to the synthesis of peptides by using a broad range of methods and strategies.
700	1		_aJensen, Knud J _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aTofteng Shelton, Pernille _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aPedersen, Søren L _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781627035453
776	0	8	_iPrinted edition: _z9781627035439
776	0	8	_iPrinted edition: _z9781493960040
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-544-6 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2013
999			_c235128 _d235128