000			03448nam a22003735i 4500
001			235131
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007			cr nn 008mamaa
008			160413s2016 xxu| s |||| 0|eng d
020			_a9781493935604
024	7		_a10.1007/978-1-4939-3560-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aImmunotherapy and Biomarkers in Neurodegenerative Disorders _cedited by Martin Ingelsson, Lars Lannfelt.
250			_a1st edition 2016
264		1	_aNew York, NY _bSpringer International Publishing _c2016
300			_a1 recurso en línea (X, 289 páginas) _b40 ilustraciones, 32 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aImmunotherapy Against Amyloid-β in Alzheimer's Disease: An Overview -- Active Immunization Against the Amyloid-β Peptide -- Immunotherapy Against N-Truncated Amyloid-β Oligomers -- Immunotherapy Against Amyloid-β Protofibrils: Opportunities and Challenges -- Immunotherapy Against α-Synuclein Pathology -- Extracellular α-Synuclein as a Target for Immunotherapy -- Immunotherapy of Parkinson's Disease -- Tau Immunotherapy -- Active and Passive Immunotherapy Against Tau: Effects and Potential Mechanisms -- Immunotherapy on Experimental Models for Huntington's Disease -- Cerebrospinal Fluid Biomarkers in Alzheimer's Disease -- Volumetric MRI as a Diagnostic Tool in Alzheimer's Disease -- PET Imaging as a Diagnostic Tool in Alzheimer´s Disease -- Αlpha-Synuclein as a Diagnostic Biomarker for Parkinson's Disease -- Imaging as a Diagnostic Tool in Parkinson's Disease -- Mass Spectrometry-Based Proteomics in Biomarker Discovery for Neurodegenerative Diseases.
520			_aThis practical volume examines a number of topics that explore the current status of immunotherapy and diagnostic markers for neurodegenerative disorders. With a focus on Alzheimer's disease, the first sections of the book examine immunotherapeutic approaches for the aforementioned disease as well as for Parkinson's disease and Huntington's disease, amongst others. The last section of the book covers the importance of biomarker techniques to catch these diseases early enough for the treatments to be most useful. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of detailed descriptions and implementation advice that will offer a smooth transition into the lab. Authoritative and useful, Immunotherapy and Biomarkers in Neurodegenerative Disorders aims to aid in the continued progress in the development of novel immune-based drugs and diagnostic tools for these devastating brain diseases.
700	1		_aIngelsson, Martin _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLannfelt, Lars _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493935581
776	0	8	_iPrinted edition: _z9781493935598
776	0	8	_iPrinted edition: _z9781493980789
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3560-4 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2016
999			_c235131 _d235131