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008			170201s2017 xxu| s |||| 0|eng d
020			_a9781493967834
024	7		_a10.1007/978-1-4939-6783-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aProtein Bioinformatics _bFrom Protein Modifications and Networks to Proteomics _cedited by Cathy H. Wu, Cecilia N. Arighi, Karen E. Ross.
250			_a1st edition 2017
264		1	_aNew York, NY _bSpringer International Publishing _c2017
300			_a1 recurso en línea (XIV, 472 páginas) _b130 ilustraciones, 127 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1558
505	0		_aProtein Bioinformatics Databases and Resources -- UniProt Protein Knowledgebase -- Tutorial on Protein Ontology Resources -- CATH-Gene3D: Generation of the Resource and its Use in Obtaining Structural and Functional Annotations for Protein Sequences -- Structure-Based Virtual Screening -- Bioinformatics Analysis of Protein Phosphorylation in Plant Systems Biology Using P3DB -- Navigating the Glycome Space and Connecting the Glycoproteome -- Impact of Nonsynonymous Single-Nucleotide Variations on Post-Translational Modification Sites in Human Proteins -- Analysis of Cysteine Redox Post-Translational Modifications in Cell Biology and Drug Pharmacology -- Analysis of Protein Phosphorylation and Its Functional Impact on Protein-Protein Interactions via Text Mining of the Scientific Literature -- Functional Interaction Network Construction and Analysis for Disease Discovery -- Prediction of Protein Interactions by Structural Matching: Prediction of PPI Networks and the Effects of Mutations on PPIs that Combines Sequence and Structural Information -- NDEx: A Community Resource for Sharing and Publishing of Biological Networks -- Bioinformatics Analysis of Functional Associations of PTMs -- Bioinformatics Analysis of PTM-Modified Protein Interaction Networks and Complexes -- iPTMnet: Integrative Bioinformatics for Studying PTM Networks -- Protein Identification from Tandem Mass Spectra by Database Searching -- Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite -- Mapping Biological Networks from Quantitative Data-Independent Acquisition Mass Spectrometry Proteomic Data: Data to Knowledge Pipelines -- Annotation of Alternatively Spliced Proteins and Transcripts with Protein-Folding Algorithms and Isoform-Level Functional Networks -- Computational and Statistical Methods for High-Throughput Mass Spectrometry Based PTMs Analysis -- Cross-Species PTM Mapping from Phosphoproteomic Data. .
520			_aThis volume introduces bioinformatics research methods for proteins, with special focus on protein post-translational modifications (PTMs) and networks. This book is organized into four parts and covers the basic framework and major resources for analysis of protein sequence, structure, and function; approaches and resources for analysis of protein PTMs, protein-protein interactions (PPIs) and protein networks, including tools for PPI prediction and approaches for the construction of PPI and PTM networks; and bioinformatics approaches in proteomics, including computational methods for mass spectrometry-based proteomics and integrative analysis for alternative splice isoforms, for functional discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory or computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Protein Bioinformatics: From Protein Modifications and Networks to Proteomics is a valuable resource for readers who wish to learn about state-of-the-art bioinformatics databases and tools, novel computational methods, and future trends in protein and proteomic data analysis in systems biology. This book is useful to researchers who work in the biotechnology and pharmaceutical industries, and in various academic departments, such as biological and medical sciences and computer sciences and engineering.
700	1		_aWu, Cathy H _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aArighi, Cecilia N _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aRoss, Karen E _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493967810
776	0	8	_iPrinted edition: _z9781493967827
776	0	8	_iPrinted edition: _z9781493982998
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-6783-4 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2017
999			_c235172 _d235172