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020 _a9781493929870
024 7 _a10.1007/978-1-4939-2987-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aSingle Cell Protein Analysis
_bMethods and Protocols
_cedited by Anup K. Singh, Aarthi Chandrasekaran.
250 _a1st edition 2015
264 1 _aNew York, NY
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (XI, 254 páginas)
_b
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1346
505 0 _aSingle-Cell Western Blotting.- A Microfluidic Device for Immunoassay-Based Protein Analysis of Single E. Coli Bacteria -- Enzyme-Linked ImmunoSpot (ELISpot) for Single Cell Analysis.-     Photocleavable DNA Barcoding Antibodies for Multiplexed Protein Analysis in Single Cells.- Genome-Wide Analysis of Protein and mRNA Copy Numbers in Single Escherichia Coli Cells with Single-Molecule Sensitivity.- Microfluidic Flow Cytometry for Single Cell Protein Analysis.- Microfluidic Image Cytometry for Single Cell Phenotyping of Human Pluripotent Stem Cells.- Characterizing Phenotypes and Signaling Networks of Single Human Cells by Mass Cytometry.- Multiplex Peptide-MHC Tetramer Staining with Mass Cytometry.- Imaging and Mapping of Tissue Constituents at the Single Cell Level Using MALDI MSI and Quantitative Laser Scanning Cytometry.- SPLIFF: A Single Cell Method to Map Protein-Protein Interactions in Time and Space.- Microfluidic Proximity Ligation Assay for Profiling Signaling Networks with Single-Cell Resolution.- Dynamics and Interactions of Individual Proteins in the Membrane of Single, Living Cells.- Microfluidics Enabled Enzyme Activity Measurement in Single Cells -- Microfluidic Chemical Cytometry for Enzyme Assays of Single Cells.- Quantitative Detection of Nucleocytoplasmic Transport of Native Proteins in Single Cells.
520 _aThis volume highlights recent developments in flow cytometry, affinity assays, imaging, mass spectrometry, microfluidics and other technologies that enable analysis of proteins at the single cell level. The book also includes chapters covering a suite of biochemical and biophysical methods capable of making an entire gamut of proteomic measurements, including analysis of protein abundance or expression, protein interaction networks, post-translational modifications, translocation, and enzymatic activity. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Single Cell Protein Analysis: Methods and Protocols is useful to researchers and students in biological and biomedical sciences who have an interest in proteomic measurements in cells.
700 1 _aSingh, Anup K
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aChandrasekaran, Aarthi
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493929863
776 0 8 _iPrinted edition:
_z9781493929887
776 0 8 _iPrinted edition:
_z9781493949434
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2987-0
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2015
999 _c235215
_d235215