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020 _a9781597454476
024 7 _a10.1007/978-1-59745-447-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aInflammation and Cancer
_bMethods and Protocols: Volume 1, Experimental Models and Practical Approaches
_cedited by Serguei V. Kozlov.
250 _a1st edition 2009
264 1 _aTotowa, NJ
_bHumana Press
_c2009
300 _a1 recurso en línea (XIV, 378 páginas)
_b75 ilustraciones
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v511
505 0 _aExperimental Approaches to Study Chronic Inflammation - Related Carcinogenesis -- Collection and Preparation of Rodent Tissue Samples for Histopathological and Molecular Studies in Carcinogenesis -- Biomarkers of Cell Proliferation in Carcinomas: Detection of Angiogenesis and Infiltrated Leukocytes -- Assessment of Local Proteolytic Milieu as a Factor in Tumor Invasiveness and Metastasis Formation: In Vitro Collagen Degradation and Invasion Assays -- Cytokine Multiplex Analysis -- Approaches to Determine Expression of Inflammatory Cytokines -- Selective Immortalization of Tumor-Specific T Cells to Establish Long-Term T-Cell Lines Maintaining Primary Cell Characteristics -- YKL-40: A Novel Marker Shared by Chronic Inflammation and Oncogenic Transformation -- Angiogenesis Links Chronic Inflammation with Cancer -- Inflammatory Bowel Disease: A Model of Chronic Inflammation-Induced Cancer -- Oncogenic Potential of Inflammation Induced by Viral and Bacterial Infections -- Gastric Carcinogenesis and Helicobacter pylori Infection -- Helicobacter -Based Mouse Models of Digestive System Carcinogenesis -- Screening for Molecular Markers of Cervical Papillomavirus Infection: Overview of Methods and Their Clinical Implications -- Screening for Epstein-Barr Virus in Hodgkin's Lymphoma -- A Hepatitis C Virus Xenograft Mouse Efficacy Model -- Gene Expression Profiling in Cervical Cancer: Identification of Novel Markers for Disease Diagnosis and Therapy -- Detection and Genotyping Analysis of Human Papillomavirus Isolates from Liquid-Based Cervical Cytology Specimens.
520 _aAccording to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 1, Experimental Models and Practical Approaches provides an overview of a spectrum of techniques developed to analyze the outcomes of inflammation-mediated carcinogenesis on the tissue, cellular, and molecular levels while highlighting several diagnostic aspects, such as biomarker discovery and molecular signatures evaluation. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.
700 1 _aKozlov, Serguei V
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781607612766
776 0 8 _iPrinted edition:
_z9781617379239
776 0 8 _iPrinted edition:
_z9781934115145
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-447-6
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2009
999 _c235242
_d235242