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020 _a9781627033923
024 7 _a10.1007/978-1-62703-392-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aMass Spectrometry Data Analysis in Proteomics
_cedited by Rune Matthiesen.
250 _a2nd edition 2013
264 1 _aTotowa, NJ
_bHumana Press
_c2013
300 _a1 recurso en línea (X, 405 páginas)
_b93 ilustraciones, 59 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1007
505 0 _aIntroduction to Mass Spectrometry-Based Proteomics -- LC-MS Spectra Processing -- Isotopic Distributions -- Retention Time Prediction and Protein Identification -- Algorithms for Database Dependent Search of MSMS Data -- Interpretation of Tandem Mass Spectra of Post-Translationally Modified Peptides -- Improving Peptide Identification Using Empirical Scoring Systems -- Methods and Algorithms for Quantitative Proteomics by Mass Spectrometry -- Computational Approaches to Selected Reaction Monitoring (SRM) Assay Design -- Feature Selection and Machine Learning with Mass Spectrometry Data -- Considerations in the Analysis of Hydrogen Exchange Mass Spectrometry Data -- Permethylated N-Glycan Analysis with Mass Spectrometry -- Mass Spectrometry Methods for Studying Glycosylation in Cancer -- Proteomics Data Exchange and Storage: The Need for Common Standards and Public Repositories -- Tools for Protein Post Translational Modifications Analysis: FAK, A Case Study -- Proteomic Strategies to Characterize Signaling Pathways -- Simple Proteomics Data Analysis in the Object-Oriented PowerShell.
520 _aSince the publishing of the first edition, the methodologies and instrumentation involved in the field of mass spectrometry-based proteomics has improved considerably.  Fully revised and expanded, Mass Spectrometry Data Analysis in Proteomics, Second Edition presents expert chapters on specific MS-based methods or data analysis strategies in proteomics. The volume covers data analysis topics relevant for quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards, among other topics.  Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Updated and authoritative, Mass Spectrometry Data Analysis in Proteomics, Second Edition serves as a detailed guide for all researchers seeking to further our knowledge in the field of proteomics.
700 1 _aMatthiesen, Rune
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781627033930
776 0 8 _iPrinted edition:
_z9781627033916
776 0 8 _iPrinted edition:
_z9781493959952
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-392-3
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2013
999 _c235255
_d235255