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020 _a9781493966134
024 7 _a10.1007/978-1-4939-6613-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aBioinformatics
_bVolume II: Structure, Function, and Applications
_cedited by Jonathan M. Keith.
250 _a2nd edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (XI, 426 páginas)
_b88 ilustraciones, 26 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1526
505 0 _a3D Computational Modeling of Proteins Using Sparse Paramagnetic NMR Data -- Inferring Function from Homology -- Inferring Functional Relationships from Conservation of Gene Order -- Structural and Functional Annotation of Long Non-Coding RNAs -- Construction of Functional Gene Networks Using Phylogenetic Profiles -- Inferring Genome-Wide Interaction Networks -- Integrating Heterogeneous Datasets for Cancer Module Identification -- Metabolic Pathway Mining -- Analysis of Genome-Wide Association Data -- Adjusting for Familial Relatedness in the Analysis of GWAS Data -- Analysis of Quantitative Trait Loci -- High-Dimensional Profiling for Computational Diagnosis -- Molecular Similarity Concepts for Informatics Applications -- Compound Data Mining for Drug Discovery -- Studying Antibody Repertoires with Next-Generation Sequencing -- Using the QAPgrid Visualization Approach for Biomarker Identification of Cell-Specific Transcriptomic Signatures -- Computer-Aided Breast Cancer Diagnosis with Optimal Feature Sets: Reduction Rules and Optimization Techniques -- Inference Method for Developing Mathematical Models of Cell Signaling Pathways Using Proteomic Datasets -- Clustering -- Parameterized Algorithmics for Finding Exact Solutions of NP-Hard Biological Problems -- Information Visualization for Biological Data.
520 _aThis second edition provides updated and expanded chapters covering a broad sampling of useful and current methods in the rapidly developing and expanding field of bioinformatics. Bioinformatics, Volume II: Structure, Function, and Applications, Second Edition is comprised of three sections: Structure, Function, Pathways and Networks; Applications; and Computational Methods. The first section examines methodologies for understanding biological molecules as systems of interacting elements. The Applications section covers numerous applications of bioinformatics, focusing on analysis of genome-wide association data, computational diagnostic, and drug discovery. The final section describes four broadly applicable computational methods that are important to this field. These are: modeling and inference, clustering, parameterized algorithmics, and visualization. As a volume in the highly successful Methods in Molecular Biology series, chapters feature the kind of detail and expert implementation advice to ensure positive results. Comprehensive and practical, Bioinformatics, Volume II: Structure, Function, and Applications is an essential resource for graduate students, early career researchers, and others who are in the process of integrating new bioinformatics methods into their research. .
700 1 _aKeith, Jonathan M
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493966110
776 0 8 _iPrinted edition:
_z9781493966127
776 0 8 _iPrinted edition:
_z9781493982509
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-6613-4
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2017
999 _c235284
_d235284