000			03490nam a22003735i 4500
001			235316
003			ES-VaUE
005			20221220020657.0
007			cr nn 008mamaa
008			161102s2017 xxu| s |||| 0|eng d
020			_a9781493965397
024	7		_a10.1007/978-1-4939-6539-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aCancer Gene Networks _cedited by Usha Kasid, Robert Clarke.
250			_a1st edition 2017
264		1	_aNew York, NY _bSpringer International Publishing _c2017
300			_a1 recurso en línea (XII, 248 páginas) _b60 ilustraciones, 41 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1513
505	0		_aIntroduction- Cancer Gene Networks -- Emerging Methods in Chemoproteomics with Relevance to Drug Discovery -- ANXA7-GTPase as Tumor Suppressor: Mechanisms and Therapeutic Opportunities -- Experimental and Study Design Considerations for Uncovering Oncometabolites -- Targeting Deubiquitinating Enzymes and Autophagy in Cancer -- Quantitative Clinical Imaging Methods for Monitoring Intratumoral Evolution -- Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression -- Network-oriented Approaches to Anti-cancer Drug Response -- CRISPR/Cas-mediated Knockin in Human Pluripotent Stem Cells -- Complete Transcriptome RNA-Seq -- Computational Methods and Correlation of Exon-skipping Events with Splicing, Transcription and Epigenetic Factors -- Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma -- microRNA Target Prediction -- Evaluating the Delivery of Proteins to the Cytosol of Mammalian Cells -- Validation of Biomarker Proteins using Reverse Capture Protein Microarrays -- Chemical Synthesis of Activity-Based Diubiquitin Probes -- Profiling the Dual Enzymatic Activities of the Serine/Threonine Kinase IRE1α.
520			_aThis volume is a valuable and timely resource for a broad audience with interests in basic and translational cancer biology, cancer drug development, as well as in the practice of personalized oncology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Gene Networks aims to ensure successful results in the further study of this evolving and vital field. Ultimately these efforts will guide development of transformative strategies for cancer diagnosis and treatment.
700	1		_aKasid, Usha _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aClarke, Robert _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493965373
776	0	8	_iPrinted edition: _z9781493965380
776	0	8	_iPrinted edition: _z9781493982301
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-6539-7 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2017
999			_c235316 _d235316