000			03789nam a22003615i 4500
001			235351
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007			cr nn 008mamaa
008			160205s2016 xxu| s |||| 0|eng d
020			_a9781493935154
024	7		_a10.1007/978-1-4939-3515-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aBacterial Therapy of Cancer _bMethods and Protocols _cedited by Robert Hoffman.
250			_a1st edition 2016
264		1	_aNew York, NY _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XVI, 186 páginas) _b43 ilustraciones, 33 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1409
505	0		_aTumor Targeting Salmonella Typhimurium A1-R: An Overview -- Enhancement of Tumor-Targeted Delivery of Bacteria with Nitroglycerin Involving Augmentation of the ERP Effect -- Oral Delivery of Tumor-Targeting Salmonella to Treat Cancer in Mice -- Microfluidic Device to Quantify the Behavior of Therapeutic Bacteria in Three-Dimensional Tumor Tissue -- Tumor-Targeting Therapy Using Gene-Engineered Anaerobic-Nonpathogenic Bifidobacterium Longum -- Noninvasive In Vivo Imaging to Follow Bacteria Engaged in Cancer Therapy -- In Vivo Bioluminescence Imaging of Intra-Tumoral Bacteria -- Employment of Salmonella in Cancer Gene Therapy -- Development of a Targeted Gene Delivery System Using Escherichia Coli -- Isolation and Analysis of Suppressor Mutations in Tumor-Targeted msbB Salmonella -- Determination of Plasmid Segregational Stability in a Growing Bacterial Population -- Visualization of Anti-Cancer Salmonella Typhimurium Engineered for Remote-Control of Therapeutic Proteins -- Methods for Tumor Targeting with Salmonella Typhimurium A1-R -- Salmonella Typhimurium A1-R and Cell-Cycle Decoy Therapy of Cancer -- Future of Bacterial Therapy of Cancer.
520			_aThis volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.
700	1		_aHoffman, Robert _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493935130
776	0	8	_iPrinted edition: _z9781493935147
776	0	8	_iPrinted edition: _z9781493980635
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3515-4 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2016
999			_c235351 _d235351