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020 _a9781493923434
024 7 _a10.1007/978-1-4939-2343-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aGlycoinformatics
_cedited by Thomas Lütteke, Martin Frank.
250 _a1st edition 2015
264 1 _aNew York, NY
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (XVI, 506 páginas)
_b182 ilustraciones, 146 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1273
505 0 _aAnnotation of Glycomics MS and MS/MS Spectra Using the GlycoWorkbench Software Tool -- GlycoBase and autoGU: Resources for Interpreting HPLC-Glycan Data -- NMR Chemical Shift Prediction of Glycans: Application of the Computer Program CASPER in Structural Analysis -- Handling and Conversion of Carbohydrate Sequence Formats and Monosaccharide Notation -- Bacterial, Plant, and Fungal Carbohydrate Structure Databases: Daily Usage -- Using NMR Data on GLYCOSCIENCES -- Glycomic Analysis Using KEGG GLYCAN -- GlycomeDB -- Eukaryotic Glycosylation: Online Methods for Site-Prediction on Protein Sequences -- Analyzing Glycan Structure Synthesis with the Glycan Pathway Predictor (GPP) Tool -- Functional Network in Post-Translational Modifications: Glyco-Net in Glycoconjugate Data Bank -- JCGGDB: Japan Consortium for Glycobiology and Glycotechnology DataBase -- Glycan Array Data Management at Consortium for Functional Glycomics -- Analyzing Glycan Binding Patterns with the ProfilePSTMM Tool -- Exploring the Specificities of Glycan-Binding Proteins Using Glycan Array Data and the GlycoSearch Software -- Statistical Analysis of Amino Acids in the Vicinity of Carbohydrate Residues Performed by GlyVicinity -- Tools to Assist Determination and Validation of Carbohydrate 3D Structure Data -- Glyco3D : A Portal for Structural Glycosciences -- Solution Conformation of Carbohydrates: A View by Using NMR Assisted by Modeling -- Informing Saccharide Structural NMR Studies with Density Functional Theory Calculations -- Energy Maps for Glycosidic Linkage Conformations -- Conformational Analysis of Oligo- and Polysaccharides Using Molecular Dynamics Simulations -- Molecular Dynamics Simulations of Membrane- and Protein-Bound Glycolipids Using GLYCAM -- Lipopolysaccharide Membrane Building and Simulation -- Molecular Dynamics Simulations of Glycoproteins Using CHARMM -- Calculating Binding Free Energies for Protein-Carbohydrate Complexes -- Scoring Functions for AutoDock -- Structures of Glycans Bound to Receptors from Saturation Transfer Difference (STD) NMR Spectroscopy: Quantitative Analysis by Using CORCEMA-ST -- QM/MM Methods for Studying Enzymatic Reactions of Glycosyltransferases.
520 _aThis book provides current glycoinformatics methods and protocols used to support the determination of carbohydrate structures in biological samples as well as carbohydrate structure databases, the interaction of carbohydrates with proteins, and theoretical and experimental methods to study their three-dimensional structure and dynamics. Glycoinformatics explores this recently emerged field, which has come into being in order to address the needs of encoding, storing, and analyzing carbohydrate 'sequences' and their taxonomy using computers. Written in the highly successful Methods in Molecular Biology series format, chapters contain the kind of detailed description and key implementation advice to ensure successful results. Authoritative and timely, Glycoinformatics demonstrates the progress that has been achieved in glycoinformatics, which indicates that it is no longer a niche subject covered by only a few scientists but is truly coming of age.
700 1 _aLütteke, Thomas
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aFrank, Martin
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493923427
776 0 8 _iPrinted edition:
_z9781493923441
776 0 8 _iPrinted edition:
_z9781493941957
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2343-4
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2015
999 _c235397
_d235397