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020 _a9781592590742
024 7 _a10.1385/1592590748
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aHematologic Malignancies
_bMethods and Techniques
_cedited by Guy B. Faguet.
250 _a1st edition 2001
264 1 _aTotowa, NJ
_bHumana Press
_c2001
300 _a1 recurso en línea (XV, 360 páginas)
_b
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Medicine
_x1940-6037
_v55
505 0 _aCytogenetics -- Cytogenetics Analysis -- FISH Analysis -- Comparative Genomic Hybridization for the Analysis of Leukemias and Lymphomas -- Spectral Karyotyping (SKY) of Hematologic Malignancies -- Polymerase Chain Reaction -- Molecular Genetic Methods in Diagnosis and Treatment -- Detecting Monoclonal Immunoglobulin andT-Cell Receptor Gene Rearrangements in B- andT-Cell Malignancies by Polymerase Chain Reaction -- Quantifying Residual Leukemia by "Clone-Specific" Polymerase Chain Reaction -- NPM-ALK Reverse Transcriptase-Polymerase Chain Reaction for Detecting the t(2;5) of Non-Hodgkin's Lymphoma -- Flow Cytometry -- Diagnostic Flow Cytometry in Hematologic Malignancies -- Flow Cytometric Analysis of Hematologic Neoplasia -- In Situ Hybridization in Flow Cytometry -- Quantitative Fluorescence Cytometry -- Special Histopathology Stains -- Methods in Leukocyte Cytochemistry -- Immunohistochemistry in Leukemias and Lymphomas -- Molecular Genetics and Cytokines -- Apoptosis -- Cytokine Receptors.
520 _aRecent advances in molecular biology are transforming the treatment of hematologic malignancies by providing powerful new tools useful in both diagnosis and the assessment of new therapies. In Hematologic Malignancies: Methods and Techniques, a panel of acknowledged experts review many of the key molecular methods used for the diagnosis and subsequent management of hematologic malignancies. These clinically relevant techniques range from routine test procedures to highly sophisticated methods currently offered only by specialized reference laboratories, and fall into five major groups: cytogenetics, polymerase chain reaction, flow cytometry, cytochemistry and immunochemistry, and apoptosis and cytokine receptors. Presented by investigators with extensive experience, and serving not only as a reference for seasoned research and clinical laboratory personnel, but also as a guide for the less experienced, each method contains sufficient detail to ensure its successful replication. Serving both clinical and experimental needs, Hematologic Malignancies: Methods and Techniques provides an array of powerful tools that will guide clinicians- especially hematologists, oncologists, and pathologists-to better diagnose and manage their patients with hematologic malignancies, and enable researchers to assess the anticancer effect of agents that impact cancer cells at the molecular level.
700 1 _aFaguet, Guy B
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781489942166
776 0 8 _iPrinted edition:
_z9780896035430
776 0 8 _iPrinted edition:
_z9781489942159
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592590748
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2001
999 _c235423
_d235423