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008			170627s2017 xxu| s |||| 0|eng d
020			_a9781493971190
024	7		_a10.1007/978-1-4939-7119-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aCurrent Proteomic Approaches Applied to Brain Function _cedited by Enrique Santamaría, Joaquín Fernández-Irigoyen.
250			_a1st edition 2017
264		1	_aNew York, NY _bSpringer International Publishing _c2017
300			_a1 recurso en línea (XVI, 360 páginas) _b91 ilustraciones, 61 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v127
505	0		_aBrain Proteomics: Decoding Neuroproteomes using Mass-Spectrometry -- Applications of Amine-Reactive Tandem Mass Tags (TMT) in Human Neuroproteomics -- Application of Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) to Monitor Olfactory Proteomes during Alzheimer´s Disease Progression -- Protein Microarrays in Neurodegenerative Diseases -- Comprehensive Shotgun Proteomic Analyses of Oligodendrocytes using Ion Mobility and Data Independent Acquisition -- Non-Targeted Brain Lipidomics Profiling Performed by UPLC-ESI-qTOF-MS/MS -- Methods for Human Olfactory Bulb-Tissue Studies using Peptide/Protein MALDI-TOF Imaging Mass Spectrometry (MALDI-IMS) -- Neuroproteomics using Short GeLC-SWATH: From the Evaluation of Proteome Changes to the Clarification of Protein Function -- Analysis of Brain Phosphoproteome using Titanium Dioxide Enrichment and High Resolution LC-MS/MS -- N-Glycomics and N-Glycoproteomics of Human Cerebrospinal Fluid -- In Vivo Strategies to Isolate and Characterize the Neuronal Ubiquitinated Proteome -- Characterization of the Phosphoproteome and Sialoproteome in Brain Tissues by Mass Spectrometry -- Proteomic Analysis of SUMOylation in the Post-Ischemic Brain -- S-Nitrosylation in Alzheimer´s Disease using Oxidized Cysteine-Selective cPILOT -- Proteomic Analysis of Extracellular Vesicles in Neurological Diseases -- Quantitative In-Depth Profiling of the Postsynaptic Density Proteome to Understand the Molecular Mechanisms Governing Synaptic Physiology and Pathology -- Nuclear Proteomics for Exploring MK-801 Treated Oligodendrocytes to Better Understand Schizophrenia -- Localized Proteomics of Individual Neurons Isolated from Formalin-Fixed, Paraffin Embedded Tissue Sections using Laser Capture Microdissection -- Creation of Reusable Bioinformatics Workflows for Reproducible Analysis of LC-MS Proteomics Data -- Integration of Transcriptomic and Proteomic Data for Disease Insights.
520			_aThis volume focuses on protein analysis covering a wide spectrum of the utility of mass spectrometry within neurobiological disciplines. The chapters in this book discuss label (iTRAQ, TMT, protein arrays) and label-free workflows (SWATH, MALDI Imaging, and label-free quantitation). Other chapters look at experimental strategies targeted to the identification and quantitation of specific lipids and post-translational modifications, as well as proteomic workflows that focus on characterization of subcellular proteomes. The last few chapters in the book describe various bioinformatics pipelines used to analyze the molecular data derived from high-throughput transcriptomic and proteomic experiments on brain tissue. The Neuromethods series offers chapters with key advice and procedure specifics to empower the readers to successfully achieve their own scientific and experimental goals. Thorough and comprehensive, Current Proteomic Approaches Applied to Brain Function is a valuable resource for graduate students and postdoctoral fellows interested in neuroproteomics, as well as researchers looking for further insight into the growing field of mass spectrometry in neuroscience.
700	1		_aSantamaría, Enrique _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aFernández-Irigoyen, Joaquín _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493971183
776	0	8	_iPrinted edition: _z9781493971206
776	0	8	_iPrinted edition: _z9781493983902
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7119-0 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2017
999			_c235445 _d235445