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020 _a9781493970513
024 7 _a10.1007/978-1-4939-7051-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aImaging Mass Spectrometry
_bMethods and Protocols
_cedited by Laura M. Cole.
250 _a1st edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (X, 204 páginas)
_b84 ilustraciones, 68 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1618
505 0 _a'A Future Amalgamation between the Scientist and the Clinician?' -- Fresh Frozen Versus Formalin Fixed Paraffin Embedded for Mass Spectrometry Imaging -- Imaging MS of Rodent Ocular Tissues and the Optic Nerve -- MALDI-MSI of Lipids in Human Skin -- MALDI-MSI Analysis of Cytological Smears: The Study of Thyroid Cancer -- Droplet-Based Liquid Extraction for Spatially-Resolved Microproteomics Analysis of Tissue Sections -- DESI Mass Spectrometry Imaging (MSI) -- Peptide Imaging: Maximizing Peptide Yield, Optimization of the 'Peptide Mass Fingerprint' -- MALDI-MS Imaging in the Study of Glomerulonephritis -- Hierarchical Cluster Analysis to Aid Diagnostic Image Data Visualization of MS and Other Medical Imaging Modalities -- Laser Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Plant Metabolites -- Mass Spectrometry Imaging of Drugs of Abuse in Hair -- MALDI Mass Spectrometry Profiling and Imaging Applied to the Analysis of Latent Fingermarks -- ToF-SIMS Parallel Imaging MS/MS of Lipid Species in Thin Tissue Sections -- Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging -- The Future in Disease Models for Mass Spectrometry Imaging, Ethical Issues and the Way Forward. .
520 _aThis volume addresses the various techniques and novel applications of mass spectrometry imaging (MSI) and its role as a discovery tool in the field of proteomics, lipidomics, and metabolomics. The chapters in this book demonstrate how MSI can be applied to many areas of research such as clinical pathology, translational medicine, toxicology, biomarkers and response studies, and potential incorporation of MSI into forensic workflows. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Innovative and comprehensive, Imaging Mass Spectrometry: Methods and Protocols is a valuable resource for research scientists and clinicians who are interested in further studies of MSI technologies.
700 1 _aCole, Laura M
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493970506
776 0 8 _iPrinted edition:
_z9781493970520
776 0 8 _iPrinted edition:
_z9781493983780
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7051-3
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2017
999 _c235472
_d235472