000 04708nam a22003735i 4500
001 235530
003 ES-VaUE
005 20221220020711.0
007 cr nn 008mamaa
008 110414s2009 xxu| s |||| 0|eng d
020 _a9781607611578
024 7 _a10.1007/978-1-60761-157-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aProteomics
_bMethods and Protocols
_cedited by Jörg Reinders, Albert Sickmann.
250 _a1st edition 2009
264 1 _aTotowa, NJ
_bHumana Press
_c2009
300 _a1 recurso en línea (XII, 441 páginas)
_b
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v564
505 0 _ato Proteomics -- Electrophorestic Separations -- High-Resolution Two-Dimensional Electrophoresis -- Non-classical 2-D Electrophoresis -- Protein Detection and Quantitation Technologies for Gel-Based Proteome Analysis -- Mass Spectrometry and Tandem Mass Spectrometry Applications -- MALDI MS -- Capillary Electrophoresis Coupled to Mass Spectrometry for Proteomic Profiling of Human Urine and Biomarker Discovery -- A Newcomer's Guide to Nano-Liquid-Chromatography of Peptides -- Multidimensional Protein Identification Technology -- Characterization of Platelet Proteins Using Peptide Centric Proteomics -- Identification of the Molecular Composition of the 20S Proteasome of Mouse Intestine by High-Resolution Mass Spectrometric Proteome Analysis -- Quantitative Proteomics -- Liquid Chromatography-Mass Spectrometry-Based Quantitative Proteomics -- iTRAQ-Labeling of In-Gel Digested Proteins for Relative Quantification -- Electrospray Mass Spectrometry for Quantitative Plasma Proteome Analysis -- Interpretation of Mass Spectrometry Data -- Algorithms and Databases -- Shotgun Protein Identification and Quantification by Mass Spectrometry -- Analysis of Protein Modifications -- Proteomics Identification of Oxidatively Modified Proteins in Bra -- Isotope-Labeling and Affinity Enrichment of Phosphopeptides for Proteomic Analysis Using Liquid Chromatography-Tandem Mass Spectrometry -- Subcellular Proteomics -- VII Subcellular Proteomics Organelle Proteomics: Reduction of Sample Complexity by Enzymatic In-Gel Selection of Native Proteins -- Isolation of Plasma Membranes from the Nervous System by Countercurrent Distribution in Aqueous Polymer Two-Phase Systems -- Enrichment and Preparation of Plasma Membrane Proteins from Arabidopsis thaliana for Global Proteomic Analysis Using Liquid Chromatography-Tandem Mass Spectrometry -- Analysis of Protein Interactions -- Tandem Affinity Purification of Protein Complexes from Mammalian Cells by the Strep/FLAG (SF)-TAP Tag -- Sequential Peptide Affinity Purification System for the Systematic Isolation and Identification of Protein Complexes from Escherichia coli -- Bioinformatical Approaches to Detect and Analyze Protein Interactions.
520 _aSince the development of the concept of "proteomics," great progress has granted deeper insight into the cellular network, but the enormous range of protein abundance, dynamics, and interactions leaves many further challenges in the field. In Proteomics: Methods and Protocols, experts in proteomic research have contributed detailed techniques, which present an overview of the contemporary challenges and possibilities in the various areas of proteomics, as well as cutting-edge protocols that provide concrete examples for successful proteome analysis. Written in the clear and concise Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy-to-use, Proteomics: Methods and Protocols will serve as a valuable reference book for laboratories around the world and raise interest in the complex and vital field of proteomics research.
700 1 _aReinders, Jörg
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSickmann, Albert
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781607611585
776 0 8 _iPrinted edition:
_z9781607611561
776 0 8 _iPrinted edition:
_z9781627038317
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60761-157-8
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2009
999 _c235530
_d235530