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001			235533
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007			cr nn 008mamaa
008			101211s2011 xxu| s |||| 0|eng d
020			_a9781603274166
024	7		_a10.1007/978-1-60327-416-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aGenetic Epidemiology _cedited by M. Dawn Teare.
250			_a1st edition 2011
264		1	_aTotowa, NJ _bHumana Press _c2011
300			_a1 recurso en línea (XII, 242 páginas) _b
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v713
505	0		_aMolecular Genetics and Genetic Variation -- Terminology, Concepts, and Models in Genetic Epidemiology -- An Introduction to Epidemiology -- Genetic Distance and Markers Used in Linkage Mapping -- Approaches to Genetic Linkage Analysis -- Fine-Scale Structure of the Genome and Markers Used in Association Mapping -- Genome-Wide Association Studies -- Candidate Gene Association Studies -- Family-Based Association Studies -- Genome Variation: A Review of Web Resources -- Advanced Methods in Twin Studies -- Mendelian Randomization: A Tool for Assessing Causality in Observational Epidemiology -- Copy Number Variation -- Epigenetic Variation -- Modeling the Effect of Susceptibility Factors (HLA and PTPN22) in Rheumatoid Arthritis -- Coronary Artery Disease: An Example Case Study -- The Genetic Epidemiology of Obesity: A Case Study.
520			_aArising from firm foundations laid by mathematical population genetics, clinical genetics, and statistical epidemiology, genetic epidemiology attempts to identify the many components of risk attributable to genes, environments, and interactions, and the course of its research can follow many diverse paths.  In Genetic Epidemiology, the success of genome-wide association studies in their identification of hundreds of disease susceptibility loci has inspired renowned experts to contribute thorough methodologies, which aim to bring together bioinformaticians, geneticists, clinicians, statisticians, and epidemiologists in the study of this vital field.  The volume opens with chapters covering the basics; however, it quickly moves on to coverage of more specialist topics such as twin studies, Mendelian randomization, genetic association studies, more advanced areas, as well as case studies.  As a part of the highly successful Methods in Molecular Biology™ series, this work provides the detailed description of the application and analysis of the most commonly employed methods that are necessary for a firm grounding in the field.   Authoritative and cutting-edge, Genetic Epidemiology aims to provide a basic framework for crucial interdisciplinary communication and understanding suited to newcomers to the field as well as experienced researchers and graduate level students.
700	1		_aTeare, M. Dawn _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781603274159
776	0	8	_iPrinted edition: _z9781607619093
776	0	8	_iPrinted edition: _z9781493957095
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60327-416-6 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2011
999			_c235533 _d235533