000			03356nam a22003495i 4500
001			235562
003			ES-VaUE
005			20221220020712.0
007			cr nn 008mamaa
008			100301s2008 xxu| s |||| 0|eng d
020			_a9781597452052
024	7		_a10.1007/978-1-59745-205-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aPharmacogenomics in Drug Discovery and Development _cedited by Qing Yan.
250			_a1st edition 2008
264		1	_aTotowa, NJ _bHumana Press _c2008
300			_a1 recurso en línea (XIII, 487 páginas) _b
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v448
505	0		_aThe Integration of Personalized and Systems Medicine -- Applications of Microarrays and Biochips in Pharmacogenomics -- Confounding in Genetic Association Studies and Its Solutions -- Pharmacogenetics of Membrane Transporters -- Pharmacogenomics of Drug-Metabolizing Enzymes and Drug Transporters in Chemotherapy -- Pharmacogenomics of G Protein-Coupled Receptor -- G Protein-Coupled Receptors Disrupted in Human Genetic Disease -- G Protein-Coupled Receptor Pharmacogenetics -- Epigenetic Alterations of the Dopaminergic System in Major Psychiatric Disorders -- Pharmacogenomics in Alzheimer's Disease -- Pharmacogenetics of Asthma -- From SNPs to Functional Studies in Cardiovascular Pharmacogenomics -- Pharmacogenomics in Gastrointestinal Disorders -- Pharmacogenomics in Rheumatoid Arthritis -- Cancer Pharmacogenetics -- Pharmacogenomics in the Preclinical Development of Vaccines -- Pharmacogenomics in the Evaluation of Efficacy and Adverse Events During Clinical Development of Vaccines.
520			_aSince each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body. In Pharmacogenomics in Drug Discovery and Development, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies. Divided into three sections, the volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. Although not in standard Methods in Molecular Biology™ series format, the book retains the practicality and usefulness of the highly successful series. Comprehensive and up-to-date, Pharmacogenomics in Drug Discovery and Development is an ideal volume for scientists striving to transform disease treatment into disease prevention.
700	1		_aYan, Qing _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781617378256
776	0	8	_iPrinted edition: _z9781588298874
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-205-2 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2008
999			_c235562 _d235562