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001			235728
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007			cr nn 008mamaa
008			120608s2012 xxu| s |||| 0|eng d
020			_a9781617796180
024	7		_a10.1007/978-1-61779-618-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	4	_aThe Handbook of Metabolomics _cedited by Teresa Whei-Mei Fan, Andrew N. Lane, Richard M. Higashi.
250			_a1st edition 2012
264		1	_aTotowa, NJ _bHumana Press _c2012
300			_a1 recurso en línea (X, 484 páginas) _b140 ilustraciones, 43 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aIntroduction to Metabolomics -- Considerations of Sample Preparation for Metabolomics Investigation -- Clinical Aspects of Metabolomics -- Structural Mass Spectrometry for Metabolomics -- Metabolomic Applications of Inductively Coupled Plasma- Mass Spectrometry (ICP-MS) -- Principles of NMR for Applications in Metabolomics -- Novel NMR and MS Approaches to Metabolomics -- Metabolic Flux Analysis -- Introduction to Metabolic Control Analysis (MCA) -- Application of Tracer-Based Metabolomics and Flux Analysis in Targeted Cancer Drug Design -- Non-Invasive Fluxomics in Mammals by Nuclear Magnetic Resonance Spectroscopy -- Compositional Analysis of Phospholipids by Mass Spectrometry and Phosphorus-31 Nuclear Magnetic Resonance Spectroscopy -- The HumanCyc Pathway-Genome Database and Pathway Tools Software as Tools for Imaging and Analyzing Metabolomics Data -- Metabolomics-Edited Transcriptomics Analysis (META).
520			_aVital to academic researchers, the medical field, and especially to biotech and pharmaceutical scientists, metabolomics is a rapidly expanding field that will provide a key link between functional biology (phenotypes) and the inner workings of cells in tissues or whole organisms.  In The Handbook of Metabolomics, expert researchers provide readers with the current state of metabolomic development and the integration of metabolomics with transcriptomics and proteomics, illustrated by research efforts related to toxicology and pharmacology. The detailed contributions deal with topics ranging from sample preparation and considerations, both laboratory and clinical, analytical methodologies for metabolite and isotopomer profiling, metabolic flux modeling, database construction, and the integration of 'omics for systems biochemical understanding, amongst other topics.   Thorough and authoritative, The Handbook of Metabolomics serves as an ideal reference for all those who wish to further pursue this promising area of study.
700	1		_aFan, Teresa Whei-Mei _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLane, Andrew N _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aHigashi, Richard M _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781617796173
776	0	8	_iPrinted edition: _z9781617796197
776	0	8	_iPrinted edition: _z9781493960439
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-618-0 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2012
999			_c235728 _d235728