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008			100301s2001 xxu| s |||| 0|eng d
020			_a9781592591459
024	7		_a10.1385/1592591450 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aMelanoma Techniques and Protocols _bMolecular Diagnosis, Treatment, and Monitoring _cedited by Brian J. Nickoloff.
250			_a1st edition 2001
264		1	_aTotowa, NJ _bHumana Press _c2001
300			_a1 recurso en línea (XVI, 368 páginas) _b
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Medicine _x1940-6037 _v61
505	0		_aBiology -- The Many Molecular Mysteries of Melanoma -- Isolation of Tumor Suppressor Genes in Melanoma by cDNA Microarray -- Molecular Characterization of Melanoma-Derived Antigens -- Experimental Induction of Human Atypical Melanocytic Lesions and Melanoma in Ultraviolet-Irradiated Human Skin Grafted to Immunodeficient Mice -- Dissection of Immunosuppressive Effects of Ultraviolet Radiation -- Antisense Oligonucleotides as Research Tools -- Diagnosis -- Genetic Testing in Familial Melanoma -- Role of Molecular Biology in Diagnostic Pathology of Melanoma -- Identification of Altered Gene Expression Associated with Pigmentary Lesions by Differential Display Analysis -- Fluorescence In Situ Hybridization as a Tool in Molecular Diagnostics of Melanoma -- Treatment -- Antigen-Pulsed Dendritic Cell Approach to Melanoma -- Gene Therapy in Melanoma -- Use of Gene Gun for Genetic Immunotherapy -- Role of Cytokines in Pathology of Melanoma and Use of Biologic Response Modifiers in Melanoma -- Surgical Techniques for Treatment of Primary Cutaneous Melanoma -- Monitoring -- Utility of Fine-Needle Aspiration Biopsy for Prospective Analysis of Patients Undergoing Therapy for Metastatic Melanoma -- A Molecular Technique Useful in the Detection of Occult Metastases in Patients with Melanoma -- Immunoscope Analysis of T-Lymphocytes Infiltrating Melanocytic Tumors -- T-Cell Receptor Clonotype Mapping Using Denaturing Gradient Gel Electrophoresis -- Methods for Use of Peptide-MHCTetramers in Tumor Immunology.
520			_aWith the completion of the Human Genome Project, it is now possible to decipher the biochemical cascade of events that lead to melanoma, a virulent form of cancer that is currently at epidemic proportions worldwide. In Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment, and Monitoring, a broadly diverse group of researchers and clinicians offer not only reviews of the most important recent advances in melanoma oncology, tumor immunology, and pathology, but also state-of-the-art molecular techniques for probing melanoma's basic biology. These readily reproducible methods can be used to develop diagnostic approaches, therapeutics, and status monitoring of patients suffering both early- and late-stage melanoma. With emphasis on the experimental details critical to success, each method is described in step-by-step fashion by hands-on masters, often those who have developed them in their own laboratories. Notes about potential pitfalls and troubleshooting tips on how to adapt procedures to new experimental systems are also provided. Comprehensive and highly instructive, Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment, and Monitoring offers clinicians and basic scientists concerned with malignant melanoma both rich new clinical perspectives and the wide ranging experimental protocols essential for achieving more rapid breakthroughs in this near-epidemic disease.
700	1		_aNickoloff, Brian J _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781617371349
776	0	8	_iPrinted edition: _z9780896036840
776	0	8	_iPrinted edition: _z9781489942364
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592591450 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2001
999			_c235758 _d235758