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020 _a9781603275309
024 7 _a10.1007/978-1-60327-530-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aInflammation and Cancer
_bMethods and Protocols: Volume 2, Molecular Analysis and Pathways
_cedited by Serguei V. Kozlov.
250 _a1st edition 2009
264 1 _aTotowa, NJ
_bHumana Press
_c2009
300 _a1 recurso en línea (XVI, 408 páginas)
_b51 ilustraciones
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v512
505 0 _aCrossroads of Inflammation and Cancer: Molecular Aspects -- Immunohistochemical Analysis of 8-Nitroguanine, A Nitrative DNA Lesion, in Relation to Inflammation-Associated Carcinogenesis -- Molecular Analysis of Genetic Instability Caused by Chronic Inflammation -- Obesity Provides a Permissive Milieu in Inflammation-Associated Carcinogenesis: Analysis of Insulin and IGF Pathways -- Detecting and Modulating the NF-kB Activity in Human Immune Cells: Generation of Human Cell Lines with Altered Levels of NF-?B -- Inflammation-Related Aberrant Patterns of DNA Methylation: Detection and Role in Epigenetic Deregulation of Cancer Cell Transcriptome -- cDNA Microarray Analysis of Inflammatory Breast Cancer Signatures -- Analysis of the TLR/NF-?B Pathway in Antigen-Presenting Cells in Malignancies Promoted by Inflammation -- Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue -- Molecular and Cellular Approaches to Diagnostics and Drug Target Discovery In Inflammation-Related Oncogenesis -- Development of a Cell-Based Assay to Quantify the Inflammatory Potential of Test Substances and Screen Compound Libraries for Anti-cancer Drug Candidates in a High-Throughput Format -- The NF-?B Transcription Factor Pathway as a Therapeutic Target in Cancer: Methods for Detection of NF-?B Activity -- Inhibiting Proinflammatory NF-?B Signaling Using Cell-Penetrating NEMO Binding Domain Peptides -- Quantitative Measurement of Cytokine Expression in Synoviocytes Derived from Rheumatoid Arthritis Patients -- Molecular Characterization of Inflammation-Induced JNK/c-Jun Signaling Pathway in Connection with Tumorigenesis -- Molecular Characterization of STAT Signaling in Inflammation and Tumorigenesis -- Inflammation and Tumor Progression: A Lesson from TNF-?-Dependent FAK Signaling in Cholangiocarcinoma -- Cyclooxygenase Inhibitors Induce Colon Cancer Cell Apoptosis Via PPAR? ? 14-3-3? Pathway -- PPAR?/? Agonist Increases the Expression of PGE2 Receptor Subtype EP4 in Human Lung Carcinoma Cells -- Investigating Macrophage and Malignant Cell Interactions In Vitro -- Cellular Magnetic Resonance Imaging Using Superparamagnetic Anionic Iron Oxide Nanoparticles: Applications to In Vivo Trafficking of Lymphocytes and Cell-Based Anticancer Therapy -- Application of Phage Display to Discovery of Tumor-Specific Homing Peptides: Developing Strategies for Therapy and Molecular Imaging of Cancer -- Molecular Basis of Histone Deacetylase Inhibitors as New Drugs for the Treatment of Inflammatory Diseases and Cancer -- Peptide YY Mediates Inhibition of Tumor Growth and Inflammation.
520 _aAccording to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 2, Molecular Analysis and Pathways is devoted to an extensive description of experimental strategies aimed at investigating the molecular cross-talks between components of cell signaling chains and their ramifications in diagnostic development and drug target discovery. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.
700 1 _aKozlov, Serguei V
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781607612773
776 0 8 _iPrinted edition:
_z9781617379055
776 0 8 _iPrinted edition:
_z9781603275293
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60327-530-9
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2009
999 _c235763
_d235763