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020			_a9783030234171
024	7		_a10.1007/978-3-030-23417-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
041	0		_aeng
050		4	_aRC280 _b.C46 2020 EB
245	1	0	_aCentral Nervous System Metastases _cedited by Manmeet Ahluwalia, Philippe Metellus, Riccardo Soffietti
250			_aFirst edition
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2020
300			_a1 recurso en línea (XIII, 421 páginas) _b45 ilustraciones, 37 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aPREFACE -- I Epidemiology -- II Pathology and Biology -- 1 Pathology of brain metastases -- 2 Translationnal approaches -- 3 Molecular mechanisms driving brain metastases development -- 4 Genomics characterization of BM -- 5 BM cell partners and tumor microenvironment -- 6 Experimental models of Brain Metastases -- III Clinical presentation and symptom management -- 7 Clinical presentation -- 8 Epilepsy in CNS metastases -- 9 Safety, tolerability and use of steroids in CNS metastasis patients -- 10 Thrombo-embolic complications in BM patients -- IV Imaging -- 11 BM diagnosis and monitoring -- 12 Metabolic imaging of BM -- 13 Radiation necrosis and progression assessment and definition -- V Surgery -- 14 Modern surgical techniques -- 15 Quality of surgical resection assessment -- 16 Indications and emerging concepts in the era molecular biology -- VI Radiation Therapy -- 17 Stereotatic radiosurgery -- 18 WBRT -- 19 Combined radiation therapy and systemic treatment -- VII Systemic treatment -- 20 Lung -- 21 Breast.-. 22 Melanoma -- 23 Miscellaneous -- VIII Neurocognition and QoL -- IV Leptomeningeal disease -- X Prevention/Prohylaxis strategies -- XI Prognosis and prognostic models -- XII Clinical trials / Endpoints and outcome assessment. .
520	3		_aThis book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.
650		7	_2embne _9669296 _aSistema nervioso central _xCáncer
700	1		_aAhluwalia, Manmeet. _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aMetellus, Philippe. _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aSoffietti, Riccardo. _eeditor _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _9106937
776	0	8	_iPrinted edition: _z9783030234164
776	0	8	_iPrinted edition: _z9783030234188
776	0	8	_iPrinted edition: _z9783030234195
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-23417-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
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