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020 _a9783319543680
024 7 _a10.1007/978-3-319-54368-0
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRM301.37
_b.C45 2019EB
245 0 0 _aCell and Gene Therapies
_cedited by Miguel-Angel Perales, Syed A. Abutalib, Catherine Bollard.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2019.
300 _aVI, 288 páginas 12 ilustraciones, 11 ilustraciones a color
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 1 _aAdvances and Controversies in Hematopoietic Transplantation and Cell Therapy,
_x2569-1376
490 0 _aMedicine (Springer-11650)
505 0 _aHistorical perspective and current focus -- Part I: Genetically modified T cells (Chimeric antigen receptors and T cell receptors): Chimeric antigen receptor-T cells: Antigen selection, CAR development and future prospects -- Chimeric antigen receptor-T cells for leukemias in children: Methods, data and challenges -- Chimeric antigen receptor-T cells for leukemias in adults- Methods, data and challenges -- Chimeric antigen receptor-T cells for lymphomas: Methods, data and challenges -- T-cell receptors-gene modified T-cells for cancer -- Methods, data and challenges. -- Part II: Beyond chimeric antigen receptor and T-cell receptors - Data, Consensus & Challenges: Cytotoxic T cells for infections: From donor-specific to “off the shelf” -- Donor lymphocyte infusion in different transplant settings: When and how?- T-regulatory cells: Broadening applicability -- Tumor infiltrating lymphocytes: Current concepts and practices -- Part III: Beyond T-cells: Natural killer cells: What have we learned?- Dendritic cells in hematopoietic cell transplantation -- Mesenchymal stem cells: From bench to bedside and back -- Cell Therapies: Regulatory concerns and data collection -- Part IV: Gene Therapy: Gene therapy for hematologic malignancies and in transplant setting -- Gene therapy for nonmalignant disorders -- Future prospects of cell and gene therapies.
520 3 _aIn this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and gene therapies with the aim of providing trainee and practicing hematologists, including hematopoietic transplant physicians, with information that is relevant to clinical practice and ongoing research. Each chapter focuses on a particular topic, and the concise text is supported by numerous working tables, algorithms, and figures. Whenever appropriate, guidance is provided regarding the availability of potentially high-impact clinical trials. The rapid evolution of cell and gene therapies is giving rise to numerous controversies that need to be carefully addressed. In meeting this challenge, this book will appeal to all residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant patients. It will also offer a robust, engaging tool to aid vital activities in the daily work of every hematology and oncology trainee.
988 _aPrimersemestre_2019_Medicine
650 1 4 _aHematology.
_0http://scigraph.springernature.com/things/product-market-codes/H3307X
653 0 _aHematology.
653 0 _aOncology  .
700 1 _aPerales, Miguel-Angel.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aAbutalib, Syed A.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_998862
700 1 _aBollard, Catherine.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_9106937
776 0 8 _iPrinted edition:
_z9783319543673
776 0 8 _iPrinted edition:
_z9783319543697
830 0 _aAdvances and Controversies in Hematopoietic Transplantation and Cell Therapy,
_x2569-1376
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-54368-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_feng
_ggw
_h0
_el