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020 _a9783030386924
024 7 _a10.1007/978-3-030-38692-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRD123.5
_b.T68 2020 EB
245 0 0 _aTotal Marrow Irradiation :
_bA Comprehensive Review
_cedited by Jeffrey Y. C. Wong, Susanta K. Hui.
250 _aFirst edition 2020
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2020.
300 _a1 recurso en línea (VI, 196 páginas)
_b45 ilustraciones, 38 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aMedicine (Springer-11650)
505 0 _aImage Guided Total Marrow Irradiation: Past, Present and Future Directions -- Guidelines for Planning, Organ Dose Constraints and Treatment Delivery: A Systematic Review -- Radiobiologic Factors to Consider with Total Marrow Irradiation -- Dose Escalation of Total Marrow Irradiation in Advanced Acute Leukemia -- Reduced Intensity Conditioning Regimens in Combination with Total Marrow and Lymphoid Irradiation -- The Use of Total Marrow and Lymphoid Irradiation in Patients Undergoing Haplo-identical Transplants -- Combining the Benefits of Total Marrow Irradiation and ATG -- Dose Escalation of Total Marrow Irradiation in Multiple Myeloma -- Total Marrow Irradiation in Multiple Myeloma Undergoing Tandem Transplant -- Total Marrow and Lymphoid Irradiation in Non-Hodgkin's Lymphoma -- Linac-based Total Marrow Irradiation -- The Case for Larger Fraction Sizes -- Acute and Late Toxicities With Total Marrow Irradiation: A Comparison to Standard Total Body Irradiation -- Total Body Irradiation Using Intensity Modulated Radiation Therapy.
520 3 _aThis book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as conditioning for bone marrow transplantation. Detailed attention is paid to the impacts of recent advances in radiation therapy technology, functional PET and MRI, and understanding of the response of bone marrow to radiation. Full consideration is also given to the ways in which technological advances in image-guided radiation therapy have created new opportunities to treat bone marrow transplant patients with limited transplant options due to advanced disease, age, or co-morbidities. Further topics covered include the ways in which cancer stem cells and the marrow microenvironment influence response to radiation therapy and the implementation of new-generation predictive radiobiologic factors in the clinic.
650 7 _2embne
_9519857
_aMédula ósea
_xEnfermedades
700 1 _aWong, Jeffrey Y. C.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/n2017185521
700 1 _aHui, Susanta K.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783030386917
776 0 8 _iPrinted edition:
_z9783030386931
776 0 8 _iPrinted edition:
_z9783030386948
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-38692-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_zSI