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020			_a9783319917856
024	7		_a10.1007/978-3-319-91785-6 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC606 _b.H86 2019 EB
245	0	0	_aHumoral Primary Immunodeficiencies _cedited by Mario Milco D'Elios, Marta Rizzi
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2019
300			_a1 recurso en línea (X, 387 páginas 34 ilustraciones a color)
336			_2rdacontent _aTexto (visual) _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	1		_aRare Diseases of the Immune System, _x2282-6505
490	0		_aMedicine (Springer-11650)
505	0		_aPreface -- 1. B cells and the B-cell immunological synapse.-2 Mucosal B cells -- 3 CVID. – 4 LOCID. – 5 Genetics of CVID. – 6 ICOS deficiency. – 7 CD19 deficiency -- 8 CD20 deficiency. – 9 CD21 deficiency. – 10 CD81 deficiency. - 11 TACI deficiency, . – 12 LRBA deficiency. – 13 BAFF receptor deficiency. – 14 TWEAK defects. - 15 NFKB2 deficiency. – 16 WHIM syndrome. – 17 Novel humoral PID genes. – 18 Class Switch Recombination defects, -- 19 Selective IgA deficiency -- 20 IgA with IgG subclass deficiency. - 21 Isolated IgG subclass deficiency. – 22 Thymoma with immunodeficiency. – 23 PRKC delta and PI3K-delta associated diseases. – 24 Differential diagnostic in hypogammaglobulinemia. – 25 Management of Humoral primary immunodeficiencies in pediatrics -- 26 Management of Humoral primary immunodeficiencies in adults -- 27 Vaccines in humoral PID -- 28 Humoral PID and neoplasias -- 29 Humoral PID and autoimmunity. – 30 Lung involvement -- 31 Gut involvement -- Subject Index.
520	3		_aThis book presents detailed state of the art knowledge on the humoral primary immunodeficiencies (PIDs), i.e., disorders arising from impaired antibody production due to defects intrinsic to B cells or defective interaction between B and T cells. There is extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the B cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel humoral PID genes and related clinical applications, mucosal B cells, and the various clinical phenotypes of humoral PIDs. Aspects such as differential diagnosis, clinical management in children and adults, and the role of vaccines are also addressed. The authors are all recognized experts from Europe, Australia, and the United States. Humoral Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD and PhD students.
988			_aPrimersemestre_2019_Medicine
650		7	_2embne _9667061 _aInmunodeficiencia
650		7	_2embne _9160812 _aEnfermedades raras
700	1		_aD'Elios, Mario Milco. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aRizzi, Marta. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _9106937
776	0	8	_iPrinted edition: _z9783319917849
776	0	8	_iPrinted edition: _z9783319917863
830		0	_aRare Diseases of the Immune System, _x2282-6505
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-91785-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
998			_db _feng _ggw _h0 _el _zSI