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020 _a9783030207625
024 7 _a10.1007/978-3-030-20762-5
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC952.5
_b.C46 2019 EB
245 0 0 _aCentenarians :
_bAn Example of Positive Biology
_cedited by Calogero Caruso.
250 _a1st ed. 2019.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2019.
300 _a1 recurso en línea (VII, 179 páginas)
_b 13 ilustraciones, 11 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aMedicine (Springer-11650)
505 0 _aChapter 1: Chance and Causality in Ageing and Longevity -- Chapter 2: Phenotypic Aspects of Longevity -- Chapter 3: Centenarian Offspring as a Model of Successful Ageing -- Chapter 4: Individual Longevity Versus Population Longevity -- Chapter 5: Dietary Inflammatory Index in Ageing and Longevity -- Chapter 6: Genetic Signatures of Centenarians -- Chapter 7: Epigenetics and Ageing -- Chapter 8: Lifestyle Choices, Psychological Stress, and Their Impact on Aging: The Role of Telomeres -- Chapter 9: Gut Microbiota Pattern of Centenarians -- Chapter 10: The Impact of Mediterranean Diet on Longevity -- Chapter 11: Lifespan and Healthspan Extension by Nutraceuticals: An Overview. .
520 3 _aThis state-of-the-art review on longevity focuses on centenarians, studied as a model of positive biology. The extraordinary rise in the elderly population in developed countries underscores the importance of studies on ageing and longevity in order to decrease the medical, economic and social problems associated with the increased number of non-autonomous individuals affected by invalidating pathologies. Centenarians have reached the extreme limits of human life span. Those in relatively good health, who are able to perform their routine daily tasks, are the best examples of extreme longevity, representing selected individuals in which the appearance of major age-related diseases - including cancer and cardiovascular diseases - has been consistently delayed or avoided. The relationship between causality and chance is an open discussion topic in many disciplines. In particular, ageing, the related diseases, and longevity are difficult to define as a consequence of causality, chance or both. Discussing the relevance of these different factors in the attainment of longevity, the book gathers contributions on genetic, epigenetic and phenotypic aspects of centenarians. The "positive biology" approach is applied to clarify the causes of positive phenotypes, as well as to explain the biological mechanisms of health and well-being with the aim of preventing and/or reducing frailty and disability in the elderly.
650 7 _9140743
_aGeriatría
_2embne
700 1 _aCaruso, Calogero
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_9106937
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783030207618
776 0 8 _iPrinted edition:
_z9783030207632
776 0 8 _iPrinted edition:
_z9783030207649
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-20762-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_zSI