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020 _a9783030226961
024 7 _a10.1007/978-3-030-22696-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-VaUE
050 4 _aQP572
_b.A54 2019 EB
245 0 0 _aAngiotensin-(1-7) :
_bA Comprehensive Review
_cedited by Robson Augusto Souza Santos.
250 _a1st ed. 2019.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2019.
300 _a1 recurso en línea (XIII, 240 páginas)
_b 33 ilustraciones, 23 ilustraciones a color.
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aMedicine (Springer-11650)
505 0 _aINTRODUCTION -- 1.ANGIOTENSIN-(1-7) FORMATION AND METABOLISM -- Part I. TOOLS FOR STUDYING ANG-(1-7) -- 2. Pharmacological Tools-RAS -- 3. Genetic Models (ACE2 Models, MAS Models, Ang-(1-7) Models) -- Part II. ACTIONS OF ANGIOTENSIN-(1-7) -- 4. Brain (Ang-(1-7) Metabolism in the Brain, Ang-(1-7) Location in the Brain, MAS Location in the Brain, Ang-(1-7) Actions in the Brain, Cardiovascular Effects of Angiotensin-(1-7) at Specific Medullary Sites, Cardiovascular Effects of Angiotensin-(1-7) at Specific Hypothalamic Sites, Other Angiotensin-(1-7) Effects in the Brain, Neurotransmitter / Neuromodulator Effects of Ang-(1-7) -- 5. Heart (B1 Coronary vessels & Cardiomyocytes) -- 6. Ang-(1-7) and Cardioprotection -- 7. Blood Vessels -- 8. Kidney -- 9. Lung -- 10. Endocrine System -- 11. Skeletal Muscle System -- 12. Liver -- 13. Angiotensin-(1-7) and inflammation -- 14. J. Angiotensin-(-1-7) and Cancer -- 15. CONCLUDING REMARKS -- ACKNOWLEDGMENTS.
520 3 _aThis is the first book addressing in full the most important aspects of the angiotensin-(1-7), the key peptide of the protective axis and the main component in the new modulatory concept of the renin-angiotensin system. It features a detailed review of angiotensin-(1-7) and its receptor Mas, comprising the historical background, enzymatic pathways for generation, functions, integrative aspects of its protective profile, and its therapeutic potential. It also encompasses a comprehensive presentation of current knowledge about its widespread biological actions on several tissues, as well as the most recent scientific achievements, emerging from preclinical and clinical trials. Dr. Santos is a renowned researcher on the Renin-Angiontensin system, with remarkable achievements regarding the role of peptides such as alamandine and angiontensin-(1-7). He has also worked on the potential clinical applicability of angiotensin-(1-7)-related drugs for cardiovascular diseases. He has an extensive publication record in the field, including the publication of the book The Protective Arm of the Renin Angiotensin System (Academic Press, 2015). Angiotensin-(1-7) will make a unique contribution to the literature and will be an important resource for biomedical students and researchers, medical practitioners and any other professional interested in this peptide and its role in the renin-angiotensin system.
650 7 _aAngiotensina
_9671626
_2embne
700 1 _aSantos, Robson Augusto Souza
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_9106937
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783030226954
776 0 8 _iPrinted edition:
_z9783030226978
776 0 8 _iPrinted edition:
_z9783030226985
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-22696-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_zSI