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020 _a9783030167158
024 7 _a10.1007/978-3-030-16715-8
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC388.5
_b.T44 2019 EB
245 0 0 _aTherapeutic Intranasal Delivery for Stroke and Neurological Disorders
_cedited by Jun Chen, Jian Wang, Ling Wei, John H. Zhang
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2019.
300 _a1 recurso en línea (VI, 153 páginas 11 ilustraciones, 8 ilustraciones a color)
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series in Translational Stroke Research,
_x2363-958X
490 0 _aMedicine (Springer-11650)
505 0 _aPreface -- Transnasal Induction of Therapeutic Hypothermia for Neuroprotection -- Hypoxia-Primed Stem Cell Transplantation in Stroke -- Therapeutic potential of intranasal drug delivery in preclinical studies of ischemic stroke and intracerebral hemorrhage -- Intranasal Drug Delivery after Intracerebral Hemorrhage -- Intranasal Treatment in Subarachnoid Hemorrhage -- Intranasal Delivery of Therapeutic Peptides for Treatment of Ischemic Brain Injury -- Intranasal delivering method in the treatment of ischemic stroke -- Intranasal Delivery of Drugs for Ischemic Stroke Treatment: Targeting IL-17A -- Intranasal tPA application for axonal remodeling in rodent stroke and traumatic brain injury models -- Therapeutic Intranasal Delivery for Alzheimer’s disease -- Combination therapy of intranasal IGF-1 and hypothermia -- Intranasal Medication Delivery in Children for Brain Disorders -- Index.
520 3 _aThe blood-brain-barrier prevented harmful materials entering the brain and in the meantime is a barricade to therapeutic drug delivery. Intranasal drug delivery to circumvent blood-brain-barrier was developed in the past, to take advantages of a secret passage from the olfactory epithelium into the brain—bypassing the tight junctions that encapsulated the brain from blood circulation. This timely publication of Therapeutic Intranasal Delivery for Stroke and Neurological Disorders presented some of the latest advances in intranasal delivery research, including transnasal hypothermia induction, stem cell intranasal transplantation, intranasal drug delivery in ischemic and hemorrhagic models, intranasal peptides delivery, intranasal tPA application in adults and children. Editors Jun Chen, Jian Wang, Ling Wei and John Zhang are professors from University of Pittsburgh, Johns Hopkins University, Emory University and Loma Linda University in USA.
650 7 _aEnfermedades cerebrovasculares
_9670091
_2embne
_xInvestigación
653 0 _aNeurosciences.
653 0 _aNeurology.
700 1 _aChen, Jun.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988230
700 1 _aWang, Jian.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWei, Ling.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aZhang, John H.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988233
710 2 _aSpringerLink (Online service)
_9106937
776 0 8 _iPrinted edition:
_z9783030167134
776 0 8 _iPrinted edition:
_z9783030167141
830 0 _aSpringer Series in Translational Stroke Research,
_x2363-958X
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-16715-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_zSI