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020 _a9789811358777
024 7 _a10.1007/978-981-13-5877-7
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC270
_b.M65 2019 EB
245 0 0 _aMolecular Diagnostics in Cancer Patients
_cedited by Kamla Kant Shukla, Praveen Sharma, Sanjeev Misra.
264 1 _aSingapore
_bSpringer Singapore :
_bImprint: Springer
_c2019.
300 _aVIII, 341 páginas 45 ilustraciones, 43 ilustraciones a color
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 0 _aMedicine (Springer-11650)
505 0 _aIntroduction of molecular diagnostics -- Molecular Diagnostics in Bladder cancer -- Molecular Diagnostics in Lung cancer -- Molecular Diagnostics in Brain cancer -- Molecular Diagnostics in Melanoma -- Molecular Diagnostics in Breast cancer -- Molecular Diagnostics in Non-Hodgkin lymphoma -- Molecular Diagnostics in Cervical cancer -- Molecular Diagnostics in Colorectal cancer -- Molecular Diagnostics in Pancreatic cancer -- Molecular Diagnostics in Oral cancer -- Molecular Diagnostics in Prostate cancer -- Molecular Diagnostics in Kidney cancer -- Molecular Diagnostics in Skin cancer -- Molecular Diagnostics in Leukaemia -- Molecular Diagnostics in Thyroid cancer -- Molecular Diagnostics in Liver cancer -- Molecular Diagnostics in Uterine cancer -- Molecular Diagnostics in Ovarian cancer -- Pharmacogenomics Testing for Medication & Drug Response.
520 3 _aThis book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis. The book describes methods and protocols applied in molecular diagnostics. It offers pathologists and researchers providing molecular diagnostic services an array of the most recent and readily accessible reference to compare methods and techniques. Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction (qPCR), sequence-specific oligonucleotide arrays, next-generation sequencing (NGS), CGH arrays-and methodologies directed at the detection of epigenetic events, high-throughput nucleic acid and protein arrays, direct sequencing and FISH-based methodologies, currently used in the diagnosis of solid tumors. The book also includes an innovative line of treatment in relation to the molecular prognosis, diagnosis and pharmacogenomics in the actual practice of clinical findings at molecular levels. The book covers the applications of numerous genetic testing methodologies; in approximately the chronological order of discovery and high-throughput diagnosis using advanced genomic approaches to identify such genes, in the search for novel drug targets and/or key determinants of drug reactions. It also promotes a wider understanding of molecular diagnostics among physicians, medical students, and scientists in academics, industry and corporate world.
650 7 _aCáncer
_2embne
_9182544
_xDiagnóstico
650 7 _aDiagnóstico molecular
_2embne
_9158916
700 1 _aShukla, Kamla Kant.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSharma, Praveen.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMisra, Sanjeev.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_9106937
776 0 8 _iPrinted edition:
_z9789811358760
776 0 8 _iPrinted edition:
_z9789811358784
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-5877-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_zSI