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020 _a9783030048617
024 7 _a10.1007/978-3-030-04861-7
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC280
_b.G37 2019 EB
245 0 0 _aGastric Cancer In The Precision Medicine Era.
_bDiagnosis and Therapy
_cedited by Vincenzo Canzonieri, Antonio Giordano.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Humana
_c2019.
300 _aXV, 256 páginas 47 ilustraciones a color
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Clinical Pathology
_x2197-781X
490 0 _aMedicine (Springer-11650)
505 0 _aGastric Tumorigenesis: Role of Inflammation and Helicobacter Pylori -- Genetic and Epigenetic Mechanisms in Gastric Cancer -- Diagnosis and Surveillance: Endoscopic Hallmarks -- Pathological Diagnosis And Classification Of Gastric Epithelial Tumors -- Diagnostic, Prognostic, Predictive and Therapeutic Tissue Biomarkers in Gastric Cancer -- Serum Biomarkers in Gastric Cancer -- New Agents in the treatment of Advanced Gastric Cancer: Targeted Therapy and Immunotherapy -- Combined-Modality Treatment for Locally Advanced Gastric Cancer: Current Evidences and New Perspectives -- Surgical Strategies in Gastric Cancer -- From Molecular Classification to Targeted Therapy for Gastric Cancer in the Precision Medicine Era -- Non-Coding RNA in Gastric Cancer with Potential Prognostic and Predictive Role -- Immunomodulation and Immunotherapy for Gastric Cancer -- Nanomedicine in Gastric Cancer.
520 3 _aThis book provides a comprehensive, state-of-the art review and serves as an overview of the different aspects of gastric cancer. The first section aims to clarify the main aspects of tumorigenesis, such as the role of inflammation linked to the presence of H. Pylori infection, and the genetic and epigenetic mechanisms so far known. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspective will be illustrated. The second section includes the pathological and clinical features and contains information regarding the most recent tissue and serological biomarkers in these neoplasms. The three successive sections are intended to provide the “state of art” of multimodal treatment approaches to gastric cancer, i.e. standard and novel surgical aspects, common and innovative chemo and radio protocols and modern targeted therapies. Novel molecular classifications are under consideration to improve diagnostic and prognostic definitions and to prospect future treatments based on the use of immunotherapies and innovative molecules such as non-coding RNA and nanoparticles. Gastric Cancer in the Precision Medicine Era serves as a useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that helps guide patient management and stimulates investigative efforts. All chapters are written by experts in their fields and includes the most up to date scientific and clinical information.
988 _aPrimersemestre_2019_Medicine
650 7 _2embne
_9670603
_aEstómago
_xCáncer
700 1 _aCanzonieri, Vincenzo.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aGiordano, Antonio.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_926701
710 2 _aSpringerLink (Online service)
_9106937
776 0 8 _iPrinted edition:
_z9783030048600
776 0 8 _iPrinted edition:
_z9783030048624
830 0 _aCurrent Clinical Pathology,
_x2197-781X
_9133628
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-04861-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_feng
_ggw
_h0
_zSI