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020 _a9783030144050
024 7 _a10.1007/978-3-030-14405-0
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aR853
_b.Y35 2019 EB
100 1 _aYajnik, Santosh
_9670851
245 1 0 _aLandmark Trials in Oncology
_cby Santosh Yajnik.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2019.
300 _aIX, 325 páginas 120 ilustraciones, 70 ilustraciones a color
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 0 _aMedicine (Springer-11650)
505 0 _aIntroduction to Landmark Trials in Oncology -- Landmark Trials in Breast Cancer -- Landmark Trials in Lung Cancer -- Landmark Trials in Selected Genitourinary Malignancies -- Landmark Trials in Selected Gastrointestinal Cancers -- Landmark Trials in Selected Gynecologic Cancers -- Landmark Trials in Selected Head and Neck Cancers -- Landmark Trials in Selected Lymphomas -- Landmark Trials in Selected Central Nervous System Tumors -- Landmark Trials in Selected Adult Soft Tissue Sarcomas.
520 3 _aThis book describes the evolution of treatment in oncology through the lens of approximately 250 landmark clinical trials. The well-designed clinical trial is essential to the practice of medicine. There is no field that has embraced or been transformed more by the clinical trial than oncology. Each primary cancer site has a remarkable story that can be told through clinical trials. For example, patients who presented decades ago with soft tissue sarcoma of the extremities would invariably undergo limb amputation. The landmark National Cancer Institute study by Rosenberg et al. randomized patients to limb sparing surgery followed by adjuvant radiation therapy compared with limb amputation. This study helped change the standard of care by allowing most patients to retain their functioning limbs with an improvement in quality of life and no compromise in overall survival. Such major clinical trials for common malignancies including breast, prostate, lung, gastrointestinal, genitourinary, and gynecologic cancers are discussed. Because oncology is multidisciplinary, this book should be of interest for radiation oncologists, surgeons, medical oncologists, and other physicians interested in learning more about the landmark trials that have shaped oncology.
988 _aPrimersemestre_2019_Medicine
650 7 _2embne
_9144524
_aEnsayos clínicos
650 7 _2embne
_9139207
_aOncología
710 2 _aSpringerLink (Online service)
_9106937
776 0 8 _iPrinted edition:
_z9783030144043
776 0 8 _iPrinted edition:
_z9783030144067
776 0 8 _iPrinted edition:
_z9783030144074
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-14405-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_feng
_ggw
_h0
_zSI