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020 _a9783030053369
024 7 _a10.1007/978-3-030-05336-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRD598.55
_b.T57 2020 EB
245 0 0 _aTissue-Engineered Vascular Grafts
_cedited by Beat Walpoth, Helga Bergmeister, Gary Bowlin, Deling Kong, Joris Rotmans, Peter Zilla.
250 _a1st ed. 2020
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2020
300 _a1 recurso en línea (I-XXV, 588 páginas)
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aTranslation and Testing of Tissue Engineered Vascular Grafts Front Matter Pages 1-1 Clinical Applications and Limitations of Vascular Grafts Timothy Pennel, Peter Zilla Pages 3-34 Mechanical Testing of Vascular Grafts Martin Stoiber, Christian Grasl, Francesco Moscato, Heinrich Schima Pages 35-61 Preclinical In Vivo Assessment of Tissue Engineered Vascular Grafts and Selection of Appropriate Animal Models Helga Bergmeister, Bruno K. Podesser Pages 63-93 Vascular Tissue Engineering: Pathological Considerations, Mechanisms, and Translational Implications Frederick J. Schoen, Anna Mallone, Leda Klouda, Carlijn V. C. Bouten Pages 95-134 Approaches of Tissue Engineered Vascular Grafts Front Matter Pages 135-135 Synthetic Materials: Processing and Surface Modifications for Vascular Tissue Engineering William E. King III, Benjamin A. Minden-Birkenmaier, Gary L. Bowlin Pages 137-186 In Vivo Tissue-Engineered Vascular Grafts Beat H. Walpoth, Sarra de Valence, Jean-Christophe Tille, Damiano Mugnai, Tornike Sologashvili, Wojciech Mrówczyński et al. Pages 187-206 Decellularized Vascular Grafts Sotiria Toumpaniari, Andres Hilfiker, Axel Haverich, Sotirios Korossis Pages 207-269 Autologous Mandril-Based Vascular Grafts Wouter J. Geelhoed, Lorenzo Moroni, Joris I. Rotmans Pages 271-293 Advances in Cell Seeding of Tissue Engineered Vascular Grafts Justin S. Weinbaum, Darren G. Haskett, Talya F. Mandelkern, David A. Vorp Pages 295-319 Vascular Tissue Engineering: The Role of 3D Bioprinting Yu Shrike Zhang, Ali Khademhosseini Pages 321-338 Textile-Reinforced Scaffolds for Vascular Tissue Engineering Alicia Fernández-Colino, Stefan Jockenhoevel Pages 339-363 Small-Diameter Engineered Arteries: The Gel Approach Brett C. Isenberg, Chrysanthi Williams, Zeeshan H. Syedain, Robert T. Tranquillo Pages 365-376 Functionalization and Pathology of Tissue Engineered Vascular Grafts Front Matter Pages 377-377 Elastin in Vascular Grafts Richard Wang, Bente J. de Kort, Anthal I. P. M. Smits, Anthony S. Weiss Pages 379-410 The Incorporation and Release of Bioactive Molecules in Vascular Grafts Muhammad Shafiq, Hongyu Yan, Adam C. Midgley, Kai Wang, Qiang Zhao, Deling Kong Pages 411-427 Tissue Engineering to Study and Treat Cardiovascular Calcification Mark C. Blaser, Samantha K. Atkins, Elena Aikawa Pages 429-468 Vascularization of 3D Engineered Tissues Young Min Ju, Anthony Atala, James J. Yoo Pages 469-486 Clinical Application of Tissue Engineered Vascular Grafts Front Matter Pages 487-487 Off-the-Shelf Tissue-Engineered Vascular Conduits: Clinical Translation Emanuela S. Fioretta, Lisa von Boehmer, Melanie Generali, Simon P. Hoerstrup, Maximilian Y. Emmert Pages 489-531 Tissue-Engineered Vascular Grafts for Children Toshihiro Shoji, Christopher Breuer, Toshiharu Shinoka Pages 533-548 Bioengineered Human Acellular Vessels Juan Wang, Jonathan Wu, Jeffrey H. Lawson, Laura E. Niklason Pages 549-574
520 _aCardiovascular diseases are still the leading cause of death in developed countries. Revascularization procedures such as coronary artery and peripheral bypass grafts, as well as access surgery represent a 2$ billion market yearly for the US alone. Despite intense research over many decades, no clinically suitable, shelf-ready, synthetic, vascular, small-caliber graft exists. There is therefore still a quest for such a clinical vascular prosthesis for surgical revascularization procedures and access surgery. Many approaches have been tried and are currently under investigation with promising results. These range from acellular and cell-based, stable or bio-degradable, synthetic scaffolds to biological or decellularized grafts, not forgetting self-assembly technologies for in vitro or in vivo VTE. All these approaches can be further enhanced by functionalization, e.g. with growth factors and drug elution. This updatable book aims to cover all the relevant aspects of Vascular Tissue Engineering (VTE) and novel alternatives to develop vascular grafts for clinical applications. The chapters in this book cover different aspects of manufacturing scaffolds with various polymers, mechanical characteristics, degradation rates, decellularization techniques, cell sheet assembly, 3-D printing and autologous mandril-based VTE. All the necessary in vitro tests such as biocompatibility and thrombogenicity are reviewed. Pre-clinical assessment of in vivo experimental models include patency, compliance, intimal hyperplasia, inflammatory reaction, cellular ingrowth and remodeling. Finally, early clinical trials will be periodically updated regarding results, regulatory aspects and post-marketing quality assessment. Furthermore, the reader should get an insight into various approaches, technologies and methods to better understand the complexity of blood surface and cell interactions in VTE. Translational research has yielded early human applications clearly showing the enormous need of research in the field to provide better solutions for our patients and this continuously updated book will hopefully become a reference in the field for life sciences.
650 7 _2embne
_9669481
_aVálvulas cardíacas
_xCirugía
650 7 _2embne
_9273311
_aMedicina
650 0 _9513764
_aBiomedical
700 1 _aWalpoth, Beat
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aBergmeister, Helga
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aBowlin, Gary
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aKong, Deling
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRotmans, Joris
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aZilla, Peter
_eeditor
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 _aSpringerLink
_9106996
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-05336-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
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