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008			130508s2013 ne | s |||| 0|eng d
020			_a9789811568916
024	7		_a10.1007/978-981-15-6891-6 _2doi
040			_bspa _dES-VaUE
050		4	_aRC280 _b.L96 2020 EB
082	0	4	_a614.5999 _223
245	1	0	_aLynch Syndrome: _bMolecular Mechanism and Current Clinical Practice _cedited by Naohiro Tomita
250			_a1st ed. 2020
260			_aSingapore _bSpringer Nature Singapore _bImprint: Springer _c2020
300			_a1 recurso en línea (I-IX, 143 páginas) _bilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490			_aMedicine (11650)
505	0		_aMolecular Mechanism of Lynch Syndrome Kazuo Tamura Pages 1-20 Clinical Features of Lynch Syndrome Kohji Tanakaya Pages 21-32 Pathology of Lynch Syndrome-Associated Tumors Harumi Saeki, Okio Hino Pages 33-39 Immunohistochemistry for Mismatch Repair Proteins Shigeki Sekine Pages 41-52 Genetic Analysis for Lynch Syndrome Izumi Miyabe, Keisuke Tanaka, Kiwamu Akagi Pages 53-70 Lynch Syndrome-Associated Gynecological Malignancies Wataru Yamagami, Daisuke Aoki Pages 71-78 Lynch Syndrome-Associated Urological Malignancies Hisashi Hasumi, Masahiro Yao Pages 79-83 Screening for Lynch Syndrome Tatsuro Yamaguchi Pages 85-92 Surveillance Colonoscopy for Lynch Syndrome Affected Individuals Takeshi Nakajima Pages 93-102 Surgical Approach for Colorectal Cancer in Patients with Lynch Syndrome Hideyuki Ishida, Keiichiro Ishibashi, Kensuke Kumamoto Pages 103-115 Immunotherapy for Lynch Syndrome Patients Takeshi Nagasaka Pages 117-122 Chemoprevention for Lynch Syndrome-Associated Malignancies Michihiro Mutoh, Takumi Narita, Hideki Ishikawa Pages 123-132 International Collaboration for Lynch Syndrome Nagahide Matsubara Pages 133-143
520			_aThis book offers a comprehensive review of Lynch Syndrome (LS), addressing both the basic and clinical aspects of this condition. Due to the recent advances in our understanding of the genetic mechanism of LS, and to new screening methods, including universal screening and/or multi-gene panel analysis, the standard treatment strategy for patients and family members of LS have been steadily improving. In this book, experts describe the disease’s manifestations, discuss state-of-the-art diagnosis and management options, and offer a cutting-edge overview of the genetic and epigenetic basis of the syndrome. Providing essential insights into this new phase in the management of LS, this book is a valuable resource not only for colorectal surgeons, but also for general gastrointestinal clinicians, gynecologists, oncologists and all basic researchers with an interest in LS.
650		0	_aHuman genetics _9546514 _0Local
650	2	4	_aHuman Genetics _9546514 _0Local
650	2	4	_aMolecular Medicine _9547544 _0Local
650		7	_aColon (Anatomy) _xCancer _xMolecular aspects _0(OCoLC)1767252 _2fast _9548290 _0Local
650		7	_aRectum _xCancer _xGenetic aspects _0(OCoLC)1767515 _2fast _9548291 _0Local
650		7	_aRectum _xCancer _xMolecular aspects _0(OCoLC)1767518 _2fast _9548291 _0Local
650		7	_aColon (Anatomy) _xCancer _xGenetic aspects _0(OCoLC)868409 _2fast _9548290 _0Local
650		7	_aHuman genetics _0(OCoLC)963075 _2fast _9546514 _0Local
650		7	_aCáncer _xInvestigación _0comprobar BNE19901364217 _2embne _9182523
650		0	_9405021 _aMedicina _0Local
650		7	_9405021 _aMedicina _0(OCoLC)1014893 _2fast _0Local
650		0	_9139207 _aOncología _0Local
650	2	4	_9139207 _aOncología _0Local
650		7	_9139207 _aOncología _0(OCoLC)1045739 _2fast _0Local
650		0	_9141308 _aGastroenterología _0Local
650	2	4	_9141308 _aGastroenterología _0Local
650		7	_9141308 _aGastroenterología _0(OCoLC)938842 _2fast _0Local
700			_9516172 _aTomita, Naohiro
710			_aSpringerLink _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://dx.doi.org/10.1007/978-981-15-6891-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
907			_a.b12824380 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aRC280.C6 V644 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11553595 _z06-04-17
998			_db _feng _gne _h0