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999			_c8867 _d8867
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007			cr nn 008mamaa
008			150102s2014 ii | s |||| 0|eng d
020			_a9789811577932
024	7		_a10.1007/978-981-15-7793-2 _2doi
040			_bspa _dES-VaUE
050		4	_aRC915 _b.U74 2020 EB
245	1	0	_aUremic Toxins and Organ Failure _cedited by Hideyuki Saito, Takaaki Abe
250			_a1st ed. 2020
260			_aSingapore _bSpringer Nature Singapore _bImprint: Springer _c2020
300			_a1 recurso en línea (I-VIII, 180 páginas) _bIlustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490			_aMedicine (Springer-11650)
505	0		_aOverview of Uremic Toxins Toshimitsu Niwa Pages 1-15 Review: Uremic Toxins and Gut Microbiome Takehiro Suzuki, Takaaki Abe Pages 17-39 Gut Microbiota and Systemic Uremic Solute Accumulation Eikan Mishima Pages 41-51 Uremic Toxin-Related Systemic Disorders Suguru Yamamoto Pages 53-67 Uremic Toxins and Cardiovascular Disease Toyoaki Murohara Pages 69-81 Indoxyl Sulfate and Arteriosclerosis Toshiaki Nakano Pages 83-93 Uremic Toxicity and Bone in CKD Yoshiko Iwasaki, Hideyuki Yamato, Masafumi Fukagawa Pages 95-114 D-serine as a Novel Uremic Toxin Haruki Ouchi, Yosuke Hirakawa, Reiko Inagi Pages 115-129 Uremic Solutes and Sarcopenia Hiroshi Watanabe, Hiromasa Kato, Yuki Enoki, Hitoshi Maeda, Toru Maruyama Pages 131-147 Toxico-Pathological Role of Hepatic Sulfotransferase (SULT) 1A1 in Acute Kidney Injuries Hideyuki Saito Pages 149-166 Accumulation of Uremic Toxins in Systemic Organs and the Effect of AST-120 Emiko Sato Pages 167-180
520			_aThis book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney disease (CKD) patients. The human gastrointestinal tract contains trillions of microorganisms, referred to as gut microbiota, which support the host metabolism by producing nutrients, such as vitamins and short-chain fatty acids. However, they also produce various harmful uremic toxins that show renal and cardiovascular toxicity, and correlate with an increased mortality in CKD patients. The composition and balance of gut microbiota are associated with the accumulation of uremic toxins and the pathophysiology of CKD, and as such are being considered for a novel therapeutic strategy.
988			_aEBOOK, EBSPRINGER
650		0	_9405021 _aMedicina _0Local
650		0	_9512171 _aPublic health
650		7	_9405021 _aMedicina _0(OCoLC)1014893 _2fast _0Local
700			_9516492 _aSaito, Hideyuki
700			_9516493 _aAbe, Takaaki
710			_aSpringerLink _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://dx.doi.org/10.1007/10.1007/978-981-15-7793-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
907			_a.b12843921 _b10-10-17 _c23-02-15
942			_2lcc _cLE
945			_aQH588.S83 S663 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11556833 _z06-04-17
998			_db _feng _gii _h0