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020 _a9783319623283
024 7 _a10.1007/978-3-319-62328-3
_2doi
040 _aES-MaUEC
_bspa
_dES-VaUE
050 4 _aRC641.7
_b.S535 2018 EB
245 1 0 _aSickle Cell Disease and Hematopoietic Stem Cell Transplantation
_cedited by Emily Riehm Meier, Allistair Abraham, Ross M. Fasano.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2018.
300 _a1 recurso en línea (XIII, 334 páginas 21 ilustraciones, 16 ilustraciones a color)
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aMedicine (Springer-11650)
505 0 _aClinical Manifestations of Sickle Cell Disease Across the Lifespan -- Pathobiology of Sickle Cell Disease Vaso-Occlusion and Targeted Therapies -- Current Non-HSCT Related Treatments for SCD -- Risk Based Therapies for Sickle Cell Disease -- Transfusion Support of the Patient with Sickle Cell Disease Undergoing Transplantation -- Neurological Manifestations of Sickle Cell Disease and Their Impact on Allogeneic Hematopoietic Stem Cell Transplantation -- Overview of Hematopoietic Stem Cell Transplantation for Non-Malignant Diseases -- Unique Challenges of Hematopoietic Stem Cell Transplant for Sickle Cell Disease -- The Ethics of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease -- Psychosocial Care and Education of Children with Sickle Cell Disease undergoing Hematopoietic Stem Cell Transplant and their Families -- Long Term Effects of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease -- Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease -- Unrelated Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease -- Haploidentical Hematopoietic Cell Transplantation for Sickle Cell Disease -- Gene Therapy 101: The Path Toward Becoming a Realistic Cure for Patients with Sickle Cell Disease.
520 3 _aThis book provides a comprehensive, state-of-the art review of hematopoietic stem cell transplantation (HSCT) for sickle cell disease (SCD). The book reviews new data about risk prediction for severe SCD, outlines the unique challenges of HSCT for patients with SCD, profiles the supportive care guidelines for patients who are undergoing HSCT, highlights our current understanding of the best transfusion support for SCD patients prior to, during and after HSCT, and provides new perspectives about the ethics of HSCT for pediatric patients with SCD. Published in the last few years, several landmark phase III trials that utilize matched unrelated and haploidentical donors for HSCT in SCD patients are also placed in context with respect to current management. Written by experts in the field, Sickle Cell Disease and Hematopoietic Stem Cell Transplantation is a valuable resource for physicians and researchers dealing with and interested in this challenging, yet exciting, curative therapy for sickle cell disease, that will help guide patient management and stimulate investigative efforts.
650 7 _aDrepanocitemia
_9147005
_2embne
650 7 _9140122
_aHematología
_2embne
700 1 _aMeier, Emily Riehm.
_eeditor literario
_0http://id.loc.gov/authorities/names/n2018183674
_0http://viaf.org/viaf/125152561521115440466
700 1 _aAbraham, Allistair.
_eeditor literario
_0http://id.loc.gov/authorities/names/n2018183675
_0http://viaf.org/viaf/51152561524415440470
700 1 _aFasano, Ross M.
_eeditor literario
_0http://id.loc.gov/authorities/names/n2018183676
_0http://viaf.org/viaf/18152561533215440484
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_0http://viaf.org/viaf/148105729
_9106996
776 0 8 _iEdición impresa:
_z9783319623276
776 0 8 _iEdición impresa:
_z9783319623290
776 0 8 _iEdición impresa:
_z9783319872926
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-62328-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db