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008 171023s2018 gw | s |||| 0|eng d
020 _a9783319649948
024 7 _a10.1007/978-3-319-64994-8
_2doi
040 _bspa
_dES-VaUE
050 4 _aRC681
_b.R35 2018EB
100 1 _aRajamannan, Nalini M.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_988012
245 1 0 _aOsteocardiology :
_bCardiac Bone Formation
_cby Nalini M. Rajamannan.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2018.
300 _aXIV, 99 p. 22 illus. in color.
_bonline resource.
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 _aMedicine (Springer-11650)
505 0 _aOsteocardiology: Risk Factors -- Osteocardiology: Coronary Artery Calcification -- Osteocardiology: Calcific Aortic Valve Disease -- Osteocardiology: Calcific Aortic Disease -- Osteocardiology: Endochondral Bone Formation -- Osteocardiology: The Atherosclerotic Bone Paradox -- Osteocardiology: Cellular Origins of Cardiac Calcification -- Osteocardiology: LDL-Density-Gene Theory -- Osteocardiology: The LDL-Density-Mechanostat Theory -- Osteocardiology: The Go/No Go Theory For Clinical Trials.
520 _aThis book describes the field of osteocardiology, an exciting and new sub-discipline within cardiovascular science, which will become the cornerstone for defining the timing and treatment of cardiovascular calcification in the future. With the advent of large cohort databases and experimental mechanistic studies, research has elucidated evidence confirming that traditional cardiovascular risk factors are responsible for the development of atherosclerotic calcification and identified the critical elements of atherosclerosis, including foam cell formation, vascular smooth muscle cell proliferation and extracellular matrix synthesis, which over time forms bone in the heart. Osteocardiology: Cardiac Bone Formation is a practical overview of bone formation in the heart and is destined to become the cornerstone for education of medical students, residents, fellows, graduate students, physician scientists and scientists, for future research and ongoing development in medical therapies to slow or halt the progression of bone formation in the heart.
653 0 _aCardiology.
653 0 _aHuman physiology.
710 2 _aSpringerLink (Online service)
_9106996
776 0 8 _iPrinted edition:
_z9783319649931
776 0 8 _iPrinted edition:
_z9783319649955
776 0 8 _iPrinted edition:
_z9783319879215
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-64994-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db